Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3971876..3973091 Replicon chromosome
Accession NZ_CP034425
Organism Pseudomonas libanensis strain DMSP-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJJ21_RS18425 Protein ID WP_125970390.1
Coordinates 3972519..3973091 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJJ21_RS18420 Protein ID WP_047711271.1
Coordinates 3971876..3972433 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJJ21_RS18395 3967689..3968321 - 633 WP_125970385.1 glutathione S-transferase -
EJJ21_RS18400 3968538..3969614 + 1077 WP_125970386.1 aldo/keto reductase -
EJJ21_RS18410 3970355..3970774 - 420 WP_125970388.1 chemotaxis protein CheY -
EJJ21_RS18415 3970946..3971782 + 837 WP_125970389.1 acid phosphatase -
EJJ21_RS18420 3971876..3972433 + 558 WP_047711271.1 helix-turn-helix domain-containing protein Antitoxin
EJJ21_RS18425 3972519..3973091 + 573 WP_125970390.1 HD domain-containing protein Toxin
EJJ21_RS18430 3973101..3973523 - 423 WP_032896335.1 RidA family protein -
EJJ21_RS18435 3973535..3975118 - 1584 WP_125970391.1 FAD-dependent oxidoreductase -
EJJ21_RS18440 3975131..3976054 - 924 WP_069558900.1 ABC transporter substrate-binding protein -
EJJ21_RS18445 3976073..3976846 - 774 WP_047711276.1 amino acid ABC transporter ATP-binding protein -
EJJ21_RS18450 3976839..3977810 - 972 WP_047711277.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21344.46 Da        Isoelectric Point: 5.1128

>T116007 WP_125970390.1 NZ_CP034425:3972519-3973091 [Pseudomonas libanensis]
MDMEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDVP
AVNQVAFPNKGEQERRDLLLLAQSLDSPLKAEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAQPLFEALRALIDQATEQRLHAAE

Download         Length: 573 bp

>T116007 NZ_CP034425:3972519-3973091 [Pseudomonas libanensis]
ATGGACATGGAAAAAATCAAAGGCCGTCTCGACTTTCTGCGCGAGGCGGAAAAACTCAAGGATGTGCTCAGAAGCGCCCA
TACGGCTTCGGGTCGCACTGAAAGCACGGCCGAACACAGTTGGCGCCTGTGTCTGATGGCGATGGTGTTCGCTGATCAAT
TGCCCGGCCTGGACCTGCTGAAAATCCTCAAGATGTGCGTTATCCATGATTTGGGAGAAGCCATCCACGGCGATGTCCCT
GCGGTTAATCAGGTGGCCTTTCCCAACAAGGGCGAACAGGAACGGCGCGATCTGCTGCTCTTGGCGCAGTCCCTGGACAG
CCCCCTGAAAGCCGAGATCCTGACGTTATGGGATGACTACGAGAACGCGCTTTCGCCGGAAGCAAAAGCCGTCAAGGCCA
TGGACAAACTGGAGACCCTGCTGCAGCACACCCAGGGGCTGAACCCTCCCGATTTCGATTACGCCTTCAACCTGGCCTAC
GGCAAAAAACACACAGATGCCCAACCCTTGTTCGAAGCGTTGCGGGCACTGATCGATCAAGCGACAGAGCAAAGGCTCCA
CGCCGCAGAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20613.64 Da        Isoelectric Point: 9.7194

>AT116007 WP_047711271.1 NZ_CP034425:3971876-3972433 [Pseudomonas libanensis]
MPHSLLKPALPGIALRRWRLLHRIKQSHAAQLFNVTQSTISRWESGVQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRARQFSSPLADLMGQSLWRFATPQIQRVEATLEHTGWRETQAPPALEFITGSNDSNLVP
IRHSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp

>AT116007 NZ_CP034425:3971876-3972433 [Pseudomonas libanensis]
ATGCCTCACTCGTTGCTCAAGCCTGCCTTGCCCGGCATTGCGCTGCGGCGGTGGCGTTTGCTGCACCGCATCAAGCAAAG
TCATGCGGCGCAGTTGTTCAACGTCACGCAATCGACTATTTCGCGCTGGGAAAGTGGCGTACAAGCGATGGATCCGGCTG
CGCATCAGCAGCTAGAGCAGCTGTTGGCAGCCCGGCTTGATGCAGCCGCCGATCAGGCATTGGCCCGGCTGGTCAGTGAG
AGTTCGCAAGCGATGCACCTGGTATGCGACCTGACTCACCGCCTGCTCGCGTGTTCGCCCTCCCGCGCACGCCAGTTCAG
CAGCCCCCTCGCCGATCTCATGGGCCAGTCGCTGTGGCGTTTCGCAACGCCGCAAATCCAGCGGGTCGAAGCCACACTGG
AGCATACCGGCTGGCGCGAAACCCAGGCACCACCGGCCCTGGAATTCATCACTGGAAGCAACGATTCCAACCTCGTGCCC
ATACGCCACAGCCTCTGTCGCTGGACACGTATGACCCTGAGCGATGGCAGCGCAGCACGTTTGGTCGAAACACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References