116004

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1797273..1797795 Replicon chromosome
Accession NZ_CP034425
Organism Pseudomonas libanensis strain DMSP-1

Toxin (Protein)


Gene name relE Uniprot ID A0A1T1HTB9
Locus tag EJJ21_RS08550 Protein ID WP_047710304.1
Coordinates 1797273..1797566 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Y1LCT8
Locus tag EJJ21_RS08555 Protein ID WP_020301039.1
Coordinates 1797556..1797795 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJJ21_RS08515 1793962..1794495 + 534 WP_103451391.1 glycoside hydrolase family 19 protein -
EJJ21_RS08520 1794492..1795004 + 513 WP_103451390.1 lysis system i-spanin subunit Rz -
EJJ21_RS08530 1795373..1795945 + 573 WP_103451389.1 hypothetical protein -
EJJ21_RS08535 1796100..1796384 + 285 WP_103451388.1 hypothetical protein -
EJJ21_RS08540 1796369..1796632 + 264 WP_125969675.1 hypothetical protein -
EJJ21_RS08545 1796629..1796898 + 270 WP_103451387.1 hypothetical protein -
EJJ21_RS08550 1797273..1797566 - 294 WP_047710304.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EJJ21_RS08555 1797556..1797795 - 240 WP_020301039.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EJJ21_RS08565 1798449..1798703 + 255 WP_003189534.1 DUF3077 domain-containing protein -
EJJ21_RS08570 1798776..1800002 - 1227 WP_003189535.1 MFS transporter -
EJJ21_RS08575 1800246..1800533 - 288 WP_003189536.1 helix-turn-helix domain-containing protein -
EJJ21_RS08580 1800586..1801530 - 945 WP_003189537.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1755020..1818876 63856


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11624.40 Da        Isoelectric Point: 10.0977

>T116004 WP_047710304.1 NZ_CP034425:c1797566-1797273 [Pseudomonas libanensis]
MTYSLDFDARALKEWQKLGDTLRQQLKKKLVEILNNPRIEANRLHSLPDCYKIKLRSNGYRLVYQVIDQEITVFVVAVDK
RERDQAYRKASERLEQR

Download         Length: 294 bp

>T116004 NZ_CP034425:c1797566-1797273 [Pseudomonas libanensis]
ATGACCTATAGCCTTGATTTTGATGCGCGTGCATTGAAGGAATGGCAAAAGCTCGGTGACACCCTCCGTCAGCAACTCAA
AAAGAAGCTAGTCGAAATCCTGAACAACCCACGTATTGAGGCTAATCGCCTACATAGCCTGCCTGACTGCTACAAGATCA
AACTGCGTAGCAACGGGTACAGGCTGGTGTATCAAGTGATCGATCAGGAAATTACGGTGTTCGTGGTCGCCGTTGATAAA
CGTGAGCGTGATCAGGCTTATCGCAAAGCGTCTGAGCGCCTTGAACAGCGCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9027.43 Da        Isoelectric Point: 4.6017

>AT116004 WP_020301039.1 NZ_CP034425:c1797795-1797556 [Pseudomonas libanensis]
MASINIRIDDDLKTRAYLELEKLGVTPSELIRQALQYVAERGQLPFKPVLMTEEDEALMATVRERLASPQRVRVSLDDL

Download         Length: 240 bp

>AT116004 NZ_CP034425:c1797795-1797556 [Pseudomonas libanensis]
TTGGCATCTATCAACATCCGTATCGATGACGACCTGAAAACTCGCGCCTACTTGGAGCTGGAGAAACTCGGTGTCACCCC
TTCCGAACTGATACGCCAGGCGCTGCAATATGTTGCCGAGCGCGGCCAGTTGCCATTTAAGCCTGTGCTGATGACTGAAG
AGGATGAAGCCTTGATGGCGACCGTACGTGAGCGTCTTGCATCGCCTCAACGCGTGAGGGTTTCTTTGGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1T1HTB9

Antitoxin

Source ID Structure
AlphaFold DB A0A7Y1LCT8

References