Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012336..2012481 Replicon chromosome
Accession NZ_CP034415
Organism Klebsiella pneumoniae strain C789

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012372..2012474 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012336..2012481 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJJ25_RS09745 2007466..2009526 + 2061 WP_004151449.1 oligopeptidase B -
EJJ25_RS09750 2009530..2010189 - 660 WP_002911407.1 exodeoxyribonuclease X -
EJJ25_RS09755 2010268..2010498 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EJJ25_RS09760 2010611..2010985 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EJJ25_RS09765 2010989..2011858 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
EJJ25_RS09770 2011875..2012213 + 339 WP_002911404.1 YebY family protein -
- 2012336..2012481 - 146 - - Antitoxin
- 2012372..2012474 + 103 - - Toxin
EJJ25_RS09775 2012849..2012992 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EJJ25_RS09780 2013097..2014065 - 969 WP_004151446.1 VirK/YbjX family protein -
EJJ25_RS09785 2014222..2014875 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
EJJ25_RS09790 2014872..2015063 - 192 WP_002911395.1 YebW family protein -
EJJ25_RS09795 2015161..2015400 - 240 WP_002911393.1 YebV family protein -
EJJ25_RS09800 2015516..2016949 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115979 NZ_CP034415:2012372-2012474 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115979 NZ_CP034415:c2012481-2012336 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References