Detailed information of TA system TA115866

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 2885949..2886661
• Replicon: chromosome
• Accession: NZ_CP034395
• Organism: Herbaspirillum seropedicae strain AU13965

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: EJD96_RS13015
• Protein ID: WP_139971191.1
• Coordinates: 2886413..2886661 (+)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: EJD96_RS13010
• Protein ID: WP_139971190.1
• Coordinates: 2885949..2886416 (+)
• Length: 156 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EJD96_RS12990	2882261..2883145	+	885	WP_139971186.1	sugar ABC transporter permease	-
EJD96_RS12995	2883139..2884035	+	897	WP_139971187.1	ABC transporter permease subunit	-
EJD96_RS13000	2884089..2884787	-	699	WP_139971188.1	type 1 glutamine amidotransferase domain-containing protein	-
EJD96_RS13005	2884930..2885844	+	915	WP_180937446.1	LysR family transcriptional regulator	-
EJD96_RS13010	2885949..2886416	+	468	WP_139971190.1	helix-turn-helix domain-containing protein	Antitoxin
EJD96_RS13015	2886413..2886661	+	249	WP_139971191.1	hypothetical protein	Toxin
EJD96_RS13020	2886733..2886987	+	255	WP_139971192.1	hypothetical protein	-
EJD96_RS13025	2887156..2888481	-	1326	WP_013234592.1	dicarboxylate/amino acid:cation symporter	-
EJD96_RS13030	2888720..2890312	+	1593	WP_139971193.1	MCP four helix bundle domain-containing protein	-
EJD96_RS13035	2890345..2890770	-	426	WP_069374138.1	GNAT family N-acetyltransferase	-
EJD96_RS13040	2890849..2891283	-	435	WP_013234595.1	PaaI family thioesterase	-
EJD96_RS13045	2891294..2891596	-	303	WP_013234596.1	Dabb family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Helix-turn-helix domain, group 17 (84-132)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 9551.07 Da
• Isoelectric Point: 8.7727

>T115866 WP_139971191.1 NZ_CP034395:2886413-2886661 [Herbaspirillum seropedicae]
MRHSAFTALYDACVLYPAPLRDFLMCLGLCGAFRARWSRTIHEEWKRNLLINRPDLSRAQLDRTSDLMDRAIADSLGRDM
KH

Nucleotide

• Length: 249 bp

>T115866 NZ_CP034395:2886413-2886661 [Herbaspirillum seropedicae]
ATGAGGCATTCCGCTTTCACAGCCCTCTACGATGCCTGCGTGCTCTATCCCGCGCCGTTACGCGATTTTCTGATGTGCCT
TGGGCTCTGCGGCGCTTTTCGCGCACGCTGGAGCCGCACCATCCATGAGGAGTGGAAGCGCAATCTGCTGATCAATCGTC
CCGATCTCTCCAGAGCCCAGCTAGACAGGACTTCCGACCTGATGGACCGCGCCATCGCAGACAGTCTGGGGAGGGATATG
AAGCATTGA

Antitoxin

Protein

• Length: 156 a.a.
• Molecular weight: 17313.72 Da
• Isoelectric Point: 6.0644

>AT115866 WP_139971190.1 NZ_CP034395:2885949-2886416 [Herbaspirillum seropedicae]
MTHPAVSDMSLPAAKEVALAVQGQRALAAYLSTQLDTQRIQIFDDHNQAHAVELPTSALRLLMQILAELADGNAVQVVPV
HAELTTQEAADLLNVSRPHFVKLLEDGQIPFHRAGKHRRVKFADLMHYKQEREQISAQAMDELAQQAQELRMGYE

Nucleotide

• Length: 468 bp

>AT115866 NZ_CP034395:2885949-2886416 [Herbaspirillum seropedicae]
ATGACCCATCCCGCTGTGTCCGACATGTCTTTGCCCGCTGCCAAGGAGGTTGCGTTGGCTGTGCAAGGTCAACGAGCGCT
GGCCGCCTACCTGAGTACTCAGCTCGACACCCAGCGCATCCAGATCTTCGATGACCACAACCAGGCTCACGCCGTCGAGT
TGCCAACCTCGGCCTTGCGCCTGCTGATGCAGATCCTCGCCGAGTTGGCCGATGGCAATGCCGTTCAAGTGGTGCCGGTC
CACGCCGAACTCACCACCCAGGAAGCAGCCGACCTCCTCAACGTGTCGCGCCCGCATTTTGTCAAACTGCTTGAAGACGG
CCAGATTCCCTTCCATCGCGCCGGCAAGCACCGCCGCGTGAAATTTGCCGACCTGATGCACTACAAGCAGGAGCGCGAGC
AGATCAGCGCGCAGGCCATGGACGAACTGGCCCAGCAGGCTCAGGAATTGAGGATGGGATACGAATGA