Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1077711..1078474 Replicon chromosome
Accession NZ_CP034395
Organism Herbaspirillum seropedicae strain AU13965

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EJD96_RS05115 Protein ID WP_139970174.1
Coordinates 1077711..1078205 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag EJD96_RS05120 Protein ID WP_139970175.1
Coordinates 1078202..1078474 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJD96_RS05100 1073434..1074984 + 1551 WP_139970171.1 PLP-dependent aminotransferase family protein -
EJD96_RS05105 1075117..1076118 + 1002 WP_139970172.1 zinc-binding alcohol dehydrogenase family protein -
EJD96_RS05110 1076325..1077647 + 1323 WP_139970173.1 hemolysin family protein -
EJD96_RS05115 1077711..1078205 - 495 WP_139970174.1 GNAT family N-acetyltransferase Toxin
EJD96_RS05120 1078202..1078474 - 273 WP_139970175.1 DUF1778 domain-containing protein Antitoxin
EJD96_RS05125 1078565..1078966 - 402 WP_139970176.1 helix-turn-helix domain-containing protein -
EJD96_RS05130 1079339..1079527 + 189 WP_139970177.1 hypothetical protein -
EJD96_RS05135 1079615..1081372 - 1758 WP_013233118.1 gamma-glutamyltransferase -
EJD96_RS05140 1081605..1082663 - 1059 WP_069373234.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(17-145)

Antitoxin

Vibrio phage ICP1, Orf50

(6-80)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17994.81 Da        Isoelectric Point: 10.2293

>T115863 WP_139970174.1 NZ_CP034395:c1078205-1077711 [Herbaspirillum seropedicae]
VSRQLSIPQSLAAIHRLEGFDSGEPSLDDWLKRRALTNHLNGASRTFVVVDADQHVIGYYSLAAGAVTHTEATGAVRRNM
PDPVPVMVLARLAVDARAQGLKLGAALLQDAVRRVQYVAEKAGVRALLVHALNERAKQFYEHYGFLASPLHPMTLMLPLK
VRQP

Download         Length: 495 bp

>T115863 NZ_CP034395:c1078205-1077711 [Herbaspirillum seropedicae]
GTGAGTAGGCAGCTTTCCATACCGCAATCCCTCGCTGCAATCCATCGGCTCGAGGGTTTCGACAGCGGAGAACCATCGCT
GGACGATTGGCTGAAGCGACGCGCACTGACGAACCATTTAAACGGGGCCAGCCGCACTTTCGTTGTGGTCGATGCCGACC
AACACGTAATCGGGTATTACTCCTTGGCAGCGGGAGCAGTCACCCATACGGAAGCCACGGGCGCTGTCCGTCGCAACATG
CCTGATCCGGTGCCAGTGATGGTGCTTGCGAGGCTTGCGGTGGACGCTCGCGCTCAAGGCCTCAAGCTGGGCGCCGCCTT
GCTGCAAGATGCGGTAAGACGTGTGCAATATGTCGCCGAGAAAGCTGGTGTGCGAGCATTGCTCGTACATGCGTTGAACG
AACGCGCAAAGCAGTTCTATGAGCATTACGGCTTTCTTGCATCGCCTTTGCACCCGATGACGTTAATGCTTCCTCTGAAA
GTGCGTCAACCCTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10194.65 Da        Isoelectric Point: 5.1211

>AT115863 WP_139970175.1 NZ_CP034395:c1078474-1078202 [Herbaspirillum seropedicae]
MRDASINLRALPEQRDLIDRAATLLGKNRSDFMLETACERAKNIVLDQVFFSLDEDKFRQFTALLDAPQEANPGLERLMA
VKAPWSTGNK

Download         Length: 273 bp

>AT115863 NZ_CP034395:c1078474-1078202 [Herbaspirillum seropedicae]
ATGCGTGATGCCTCCATCAACTTACGCGCCCTCCCCGAGCAGCGCGACTTGATCGACCGGGCCGCTACTCTGCTGGGAAA
GAACCGCTCGGACTTTATGCTGGAAACCGCATGCGAGCGGGCAAAAAACATTGTGTTGGATCAGGTCTTTTTCAGCCTTG
ATGAAGACAAGTTCCGGCAATTCACTGCATTACTCGATGCCCCGCAAGAAGCGAATCCCGGCCTTGAACGCCTGATGGCA
GTCAAGGCTCCATGGAGCACGGGCAATAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References