Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 439528..440189 Replicon chromosome
Accession NZ_CP034395
Organism Herbaspirillum seropedicae strain AU13965

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJD96_RS02325 Protein ID WP_139969638.1
Coordinates 439776..440189 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJD96_RS02320 Protein ID WP_139969636.1
Coordinates 439528..439779 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJD96_RS02300 434596..435438 + 843 WP_069372894.1 fumarylacetoacetate hydrolase family protein -
EJD96_RS02305 435458..435913 + 456 WP_139969630.1 YaiI/YqxD family protein -
EJD96_RS02310 435925..436389 - 465 WP_139969632.1 DUF2147 domain-containing protein -
EJD96_RS02315 436546..439356 - 2811 WP_139969634.1 valine--tRNA ligase -
EJD96_RS02320 439528..439779 + 252 WP_139969636.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EJD96_RS02325 439776..440189 + 414 WP_139969638.1 type II toxin-antitoxin system VapC family toxin Toxin
EJD96_RS02330 440250..441089 - 840 WP_139969640.1 hypothetical protein -
EJD96_RS02335 441089..442708 - 1620 WP_139969642.1 hypothetical protein -
EJD96_RS02340 442745..444496 - 1752 WP_139969644.1 OmpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15355.68 Da        Isoelectric Point: 8.5679

>T115862 WP_139969638.1 NZ_CP034395:439776-440189 [Herbaspirillum seropedicae]
VSYLIDTNVLSELRRRAPDPGVLHWFSQRPAGTLYLSVLTLGELRKGIDALSDEGRKLHLLDWLETELPAFFAGRILPVD
ATVADRWGRLQAQARRPLPAIDSLLAATALTHGLSLITRNLKDFQYADLQVISPWSR

Download         Length: 414 bp

>T115862 NZ_CP034395:439776-440189 [Herbaspirillum seropedicae]
GTGAGCTACCTGATCGATACCAACGTACTGTCTGAACTACGTCGGCGTGCACCCGATCCCGGCGTGCTGCATTGGTTCTC
GCAGCGTCCTGCCGGTACGCTGTACCTGAGCGTGCTGACCTTGGGCGAGCTGCGCAAGGGGATTGATGCCTTGTCGGATG
AGGGGCGCAAGCTGCACTTGCTGGACTGGCTGGAGACCGAACTGCCCGCCTTCTTTGCCGGCCGTATCCTGCCCGTTGAC
GCTACCGTAGCGGACCGCTGGGGACGCCTGCAAGCCCAGGCCCGACGGCCCTTGCCGGCCATCGATAGTCTGCTGGCGGC
CACTGCCCTGACCCATGGGCTGAGTTTGATTACACGCAACCTGAAGGATTTTCAGTATGCGGACTTGCAAGTCATCAGCC
CGTGGAGTCGATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9547.62 Da        Isoelectric Point: 4.4978

>AT115862 WP_139969636.1 NZ_CP034395:439528-439779 [Herbaspirillum seropedicae]
MRIWQIQEAKSQFSELVREAERGGPQEITWHGRGVAVVLSKADYERLSGAGQSLVEFMQRSPLFDQDDIDLRRDDSPTRE
VDL

Download         Length: 252 bp

>AT115862 NZ_CP034395:439528-439779 [Herbaspirillum seropedicae]
ATGCGGATATGGCAGATACAAGAAGCCAAGTCCCAGTTTTCCGAGCTGGTGCGCGAGGCCGAGCGGGGTGGTCCCCAGGA
AATCACCTGGCATGGCCGTGGCGTTGCGGTGGTGCTGTCCAAGGCGGACTATGAGCGGCTGAGTGGTGCAGGCCAGTCCC
TGGTGGAGTTCATGCAGCGTTCACCGCTGTTCGACCAGGACGACATCGACCTGCGCCGGGATGACAGTCCGACCCGCGAG
GTGGACTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References