Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2170394..2170665 Replicon chromosome
Accession NZ_CP034389
Organism Escherichia coli strain RS571

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2170524..2170627 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2170394..2170665 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJH97_RS10545 2166949..2167611 - 663 WP_000944256.1 exodeoxyribonuclease X -
EJH97_RS10550 2167635..2168291 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
EJH97_RS10555 2168393..2168623 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EJH97_RS10560 2168762..2169136 + 375 WP_022645803.1 CopC domain-containing protein YobA -
EJH97_RS10565 2169140..2170012 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
EJH97_RS10570 2170025..2170366 + 342 WP_000976472.1 YebY family protein -
- 2170394..2170665 - 272 - - Antitoxin
- 2170524..2170627 + 104 - - Toxin
EJH97_RS10575 2170762..2171418 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
EJH97_RS10580 2171419..2171610 - 192 WP_001296140.1 YebW family protein -
EJH97_RS10585 2171715..2171951 - 237 WP_001295499.1 DUF1480 family protein -
EJH97_RS10590 2172069..2173508 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T115839 NZ_CP034389:2170524-2170627 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT115839 NZ_CP034389:c2170665-2170394 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References