Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1822674..1822945 Replicon chromosome
Accession NZ_CP034384
Organism Escherichia coli O157:H7 strain FRIK804

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1822804..1822907 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1822674..1822945 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJB16_RS09015 1819229..1819891 - 663 WP_000944243.1 exodeoxyribonuclease X -
EJB16_RS09020 1819915..1820571 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
EJB16_RS09025 1820673..1820903 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EJB16_RS09030 1821042..1821416 + 375 WP_000168751.1 CopC domain-containing protein YobA -
EJB16_RS09035 1821420..1822292 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
EJB16_RS09040 1822305..1822646 + 342 WP_000976483.1 YebY family protein -
- 1822674..1822945 - 272 - - Antitoxin
- 1822804..1822907 + 104 - - Toxin
EJB16_RS09045 1823042..1823698 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
EJB16_RS09050 1823699..1823890 - 192 WP_001296140.1 YebW family protein -
EJB16_RS09055 1823995..1824231 - 237 WP_001295499.1 DUF1480 family protein -
EJB16_RS09060 1824349..1825788 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T115810 NZ_CP034384:1822804-1822907 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT115810 NZ_CP034384:c1822945-1822674 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References