Detailed information of TA system TA115788

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 4010206..4010860
• Replicon: chromosome
• Accession: NZ_CP034363
• Organism: Pantoea sp. CCBC3-3-1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: EHV07_RS18665
• Protein ID: WP_147199664.1
• Coordinates: 4010206..4010613 (-)
• Length: 136 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: EHV07_RS18670
• Protein ID: WP_147199665.1
• Coordinates: 4010594..4010860 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EHV07_RS18640	4005681..4007399	-	1719	WP_147199660.1	single-stranded-DNA-specific exonuclease RecJ	-
EHV07_RS18645	4007402..4008109	-	708	WP_147199661.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
EHV07_RS18650	4008154..4009047	-	894	WP_147199662.1	site-specific tyrosine recombinase XerD	-
EHV07_RS18655	4009147..4009665	+	519	WP_147199663.1	flavodoxin FldB	-
EHV07_RS18660	4009757..4009945	-	189	Protein_3638	DNA-binding protein	-
EHV07_RS18665	4010206..4010613	-	408	WP_147199664.1	hypothetical protein	Toxin
EHV07_RS18670	4010594..4010860	-	267	WP_147199665.1	FAD assembly factor SdhE	Antitoxin
EHV07_RS18675	4011080..4012060	+	981	WP_147199666.1	tRNA-modifying protein YgfZ	-
EHV07_RS18680	4012097..4012750	-	654	WP_147199667.1	hemolysin III family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-130)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 136 a.a.
• Molecular weight: 16031.83 Da
• Isoelectric Point: 12.0062

>T115788 WP_147199664.1 NZ_CP034363:c4010613-4010206 [Pantoea sp. CCBC3-3-1]
VALWHSDLRVSWRAQWISLLLHGVVILALLLAPWPASYTVVWMLLVTLAVFECVRSQRRIRSREGDIALLEGRQMQWRRQ
QWQIHGRPWITRQAMLLTLRSAKGAQEKLWLLSDSMSEDEWRQLRQQLLNPGRRL

Nucleotide

• Length: 408 bp

>T115788 NZ_CP034363:c4010613-4010206 [Pantoea sp. CCBC3-3-1]
GTGGCCCTGTGGCACTCTGACCTGCGGGTTTCCTGGCGTGCCCAGTGGATCTCCCTGCTGCTACACGGCGTAGTGATTCT
GGCATTGCTGCTGGCCCCCTGGCCTGCCAGCTATACGGTGGTCTGGATGTTGTTGGTCACGCTTGCGGTGTTTGAATGCG
TGCGTAGCCAACGGCGGATCCGCAGTCGGGAAGGGGATATCGCGCTGCTGGAAGGGCGTCAGATGCAGTGGCGGCGACAG
CAATGGCAGATCCACGGTCGGCCGTGGATTACCCGGCAGGCAATGTTACTGACGTTACGCTCGGCGAAAGGCGCGCAGGA
GAAGCTCTGGCTGCTAAGTGACAGCATGAGCGAAGACGAATGGCGGCAGCTGCGTCAGCAGCTGCTCAATCCGGGCAGGC
GTCTCTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10457.95 Da
• Isoelectric Point: 5.0965

>AT115788 WP_147199665.1 NZ_CP034363:c4010860-4010594 [Pantoea sp. CCBC3-3-1]
MDISNKARVHWACRRGMRELDISIMPFFEFEYDSLSDSDKHLFIRLLENDDPDLFNWLMNHGEPADPELKRMVNLIQLRN
QQRGPVAL

Nucleotide

• Length: 267 bp

>AT115788 NZ_CP034363:c4010860-4010594 [Pantoea sp. CCBC3-3-1]
ATGGATATTAGTAATAAAGCTCGTGTTCACTGGGCATGTCGTCGCGGCATGCGCGAACTGGATATCTCCATCATGCCGTT
TTTTGAGTTTGAATATGACTCGCTAAGCGACAGCGACAAGCATCTGTTTATTCGACTGTTGGAAAACGACGATCCCGATC
TGTTTAACTGGTTGATGAATCATGGTGAACCCGCCGATCCTGAGCTGAAGCGCATGGTGAATTTGATTCAATTGCGAAAC
CAGCAACGTGGCCCTGTGGCACTCTGA