Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2120488..2121196 Replicon chromosome
Accession NZ_CP034363
Organism Pantoea sp. CCBC3-3-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EHV07_RS10115 Protein ID WP_147197530.1
Coordinates 2120488..2120874 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EHV07_RS10120 Protein ID WP_147197532.1
Coordinates 2120867..2121196 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHV07_RS10095 2115923..2116429 - 507 WP_147197524.1 phenolic acid decarboxylase -
EHV07_RS10100 2116528..2117397 + 870 WP_147200585.1 LysR family transcriptional regulator -
EHV07_RS10105 2117459..2119504 + 2046 WP_147197526.1 peptidyl-dipeptidase Dcp -
EHV07_RS10110 2119429..2120388 + 960 WP_147197528.1 class A beta-lactamase -
EHV07_RS10115 2120488..2120874 + 387 WP_147197530.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EHV07_RS10120 2120867..2121196 + 330 WP_147197532.1 helix-turn-helix domain-containing protein Antitoxin
EHV07_RS10125 2121310..2122467 - 1158 WP_147197534.1 FAD-dependent urate hydroxylase HpxO -
EHV07_RS10130 2122709..2123344 + 636 WP_147197536.1 aspartate/glutamate racemase family protein -
EHV07_RS10135 2123442..2123888 + 447 WP_147197539.1 DUF441 domain-containing protein -
EHV07_RS10140 2123958..2124374 + 417 WP_147197541.1 hypothetical protein -
EHV07_RS10145 2124437..2125459 + 1023 WP_147197543.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-124)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-107)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13682.78 Da        Isoelectric Point: 9.0555

>T115786 WP_147197530.1 NZ_CP034363:2120488-2120874 [Pantoea sp. CCBC3-3-1]
MEIYVLKVFDKNTKGDGIDDTILCTAAQEVINGVYEASLGGGVFKKRIPLPNTGKSGGARTVVAFKAGNCLFFMNGYAKS
GTSSYGKEIPDDALKAYKKLAADLFGMTQAQIDAQVKAKTMREVKCDG

Download         Length: 387 bp

>T115786 NZ_CP034363:2120488-2120874 [Pantoea sp. CCBC3-3-1]
ATGGAGATTTATGTTTTGAAGGTGTTCGACAAGAACACTAAAGGTGACGGCATTGATGACACCATACTGTGCACGGCCGC
ACAGGAAGTCATAAACGGGGTGTATGAGGCGAGCTTAGGTGGCGGTGTATTTAAGAAACGCATCCCGCTTCCTAACACGG
GTAAAAGCGGTGGGGCACGTACGGTTGTTGCGTTTAAGGCAGGAAATTGCCTGTTCTTTATGAACGGTTATGCGAAGTCA
GGCACCAGCAGTTATGGCAAAGAGATTCCGGATGATGCTCTTAAAGCCTATAAAAAACTTGCCGCTGATTTGTTTGGTAT
GACACAAGCGCAGATTGACGCTCAAGTGAAAGCGAAAACGATGCGAGAGGTAAAATGCGATGGTTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12322.35 Da        Isoelectric Point: 7.2048

>AT115786 WP_147197532.1 NZ_CP034363:2120867-2121196 [Pantoea sp. CCBC3-3-1]
MVDHLKDLQEMAHEMVPQGGISEDTVNYIDARVKLRELRAQLPAIIEMNGEAIRALRGRFNLSQAMLAEYVNMSVMTVSK
WERGEKKPNGAALRVLSTLLEKGPEVFRI

Download         Length: 330 bp

>AT115786 NZ_CP034363:2120867-2121196 [Pantoea sp. CCBC3-3-1]
ATGGTTGATCATCTAAAAGATTTGCAAGAAATGGCGCATGAAATGGTCCCTCAAGGCGGCATTTCTGAAGACACAGTAAA
CTACATTGATGCGCGGGTGAAACTGCGCGAACTGCGCGCTCAGCTGCCAGCCATTATCGAGATGAATGGTGAGGCGATCC
GCGCGCTGCGTGGCCGCTTTAATCTCAGCCAGGCCATGCTGGCTGAGTACGTGAATATGTCTGTTATGACTGTTTCAAAA
TGGGAAAGAGGGGAGAAAAAACCGAACGGTGCAGCTCTCCGTGTGCTGAGCACTCTCCTTGAAAAAGGCCCGGAAGTTTT
CAGGATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References