Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 1266522..1267152 Replicon chromosome
Accession NZ_CP034363
Organism Pantoea sp. CCBC3-3-1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag EHV07_RS05875 Protein ID WP_147195990.1
Coordinates 1266522..1266698 (+) Length 59 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag EHV07_RS05880 Protein ID WP_147195992.1
Coordinates 1266745..1267152 (+) Length 136 a.a.

Genomic Context

EHV07_RS05815EHV07_RS05820EHV07_RS05825EHV07_RS05830EHV07_RS05835EHV07_RS05840EHV07_RS05845EHV07_RS05850EHV07_RS05855EHV07_RS05860EHV07_RS05875EHV07_RS05880EHV07_RS05885EHV07_RS05890EHV07_RS05900EHV07_RS05905EHV07_RS05915EHV07_RS05920EHV07_RS05925EHV07_RS05935EHV07_RS05870EHV07_RS05930
Location: 1261677..1261955 (279 bp)
Type: Others
Protein ID: WP_147195963.1
Location: 1261952..1262131 (180 bp)
Type: Others
Protein ID: WP_147195965.1
Location: 1262135..1262581 (447 bp)
Type: Others
Protein ID: WP_147195969.1
Location: 1262581..1262955 (375 bp)
Type: Others
Protein ID: WP_147200539.1
Location: 1262964..1263551 (588 bp)
Type: Others
Protein ID: WP_147195973.1
Location: 1263548..1263835 (288 bp)
Type: Others
Protein ID: WP_147195975.1
Location: 1263819..1263989 (171 bp)
Type: Others
Protein ID: WP_147195978.1
Location: 1263986..1264183 (198 bp)
Type: Others
Protein ID: WP_168199597.1
Location: 1264378..1264953 (576 bp)
Type: Others
Protein ID: WP_147195982.1
Location: 1265123..1265737 (615 bp)
Type: Others
Protein ID: WP_147195984.1
Location: 1266522..1266698 (177 bp)
Type: Toxin
Protein ID: WP_147195990.1
Location: 1266745..1267152 (408 bp)
Type: Antitoxin
Protein ID: WP_147195992.1
Location: 1267381..1267731 (351 bp)
Type: Others
Protein ID: WP_147200540.1
Location: 1267718..1268155 (438 bp)
Type: Others
Protein ID: WP_147195994.1
Location: 1268444..1268740 (297 bp)
Type: Others
Protein ID: WP_168199598.1
Location: 1268744..1268980 (237 bp)
Type: Others
Protein ID: WP_147196001.1
Location: 1269255..1270142 (888 bp)
Type: Others
Protein ID: WP_147196003.1
Location: 1270150..1270401 (252 bp)
Type: Others
Protein ID: WP_147196005.1
Location: 1270391..1270771 (381 bp)
Type: Others
Protein ID: WP_147196007.1
Location: 1271366..1271938 (573 bp)
Type: Others
Protein ID: WP_147196011.1
Location: 1266030..1266236 (207 bp)
Type: Others
Protein ID: WP_147195988.1
Location: 1270899..1271345 (447 bp)
Type: Others
Protein ID: WP_147196009.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EHV07_RS058151261677..1261955+279WP_147195963.1hypothetical protein-
EHV07_RS058201261952..1262131+180WP_147195965.1hypothetical protein-
EHV07_RS058251262135..1262581+447WP_147195969.1hypothetical protein-
EHV07_RS058301262581..1262955+375WP_147200539.1ASCH domain-containing protein-
EHV07_RS058351262964..1263551+588WP_147195973.1S-adenosylmethionine-binding protein-
EHV07_RS058401263548..1263835+288WP_147195975.1hypothetical protein-
EHV07_RS058451263819..1263989+171WP_147195978.1NinE family protein-
EHV07_RS058501263986..1264183+198WP_168199597.1hypothetical protein-
EHV07_RS058551264378..1264953+576WP_147195982.1recombination protein NinG-
EHV07_RS058601265123..1265737+615WP_147195984.1hypothetical protein-
EHV07_RS058701266030..1266236-207WP_147195988.1hypothetical protein-
EHV07_RS058751266522..1266698+177WP_147195990.1type II toxin-antitoxin system HicA family toxinToxin
EHV07_RS058801266745..1267152+408WP_147195992.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
EHV07_RS058851267381..1267731+351WP_147200540.1phage holin, lambda family-
EHV07_RS058901267718..1268155+438WP_147195994.1lysozyme-
EHV07_RS059001268444..1268740+297WP_168199598.1peptidase-
EHV07_RS059051268744..1268980+237WP_147196001.1hypothetical protein-
EHV07_RS059151269255..1270142+888WP_147196003.1hypothetical protein-
EHV07_RS059201270150..1270401+252WP_147196005.1hypothetical protein-
EHV07_RS059251270391..1270771+381WP_147196007.1hypothetical protein-
EHV07_RS059301270899..1271345-447WP_147196009.1hypothetical protein-
EHV07_RS059351271366..1271938+573WP_147196011.1terminase small subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage-acrB / acrA1179950..1310593130643


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(5-57)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-62)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6709.87 Da        Isoelectric Point: 10.8214

>T115785 WP_147195990.1 NZ_CP034363:1266522-1266698 [Pantoea sp. CCBC3-3-1]
VKQSEFQRWLAAQGAEFKNGTNHLKIYLNDKQTIMPRHPGKEIPEPLRKAILKQLGLK

Download         Length: 177 bp

>T115785 NZ_CP034363:1266522-1266698 [Pantoea sp. CCBC3-3-1]
GTGAAGCAAAGCGAGTTTCAACGTTGGCTTGCAGCGCAAGGGGCAGAATTTAAGAACGGCACAAACCACCTTAAAATCTA
CCTGAACGACAAGCAGACGATAATGCCGAGGCATCCGGGGAAGGAAATACCGGAGCCGCTGAGAAAAGCGATTCTCAAGC
AACTCGGTCTTAAATAA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14631.65 Da        Isoelectric Point: 4.2606

>AT115785 WP_147195992.1 NZ_CP034363:1266745-1267152 [Pantoea sp. CCBC3-3-1]
MRYPVTLDCDDTGCAVLFPDIPEAVTGGDTREEALAMAQDALVTAFDFYFEDRREVPPPSSEGEAFVEVPASVAAKVLLL
NAVVQAGVTNAELARMIDTRPQEITRVFDLHHSTKIDTIQKALSALGKRLELAAV

Download         Length: 408 bp

>AT115785 NZ_CP034363:1266745-1267152 [Pantoea sp. CCBC3-3-1]
ATGAGATACCCAGTAACATTAGATTGTGACGATACGGGATGCGCAGTGCTGTTTCCTGACATCCCGGAAGCGGTGACGGG
CGGCGATACCAGAGAAGAGGCGTTAGCAATGGCGCAAGACGCTCTGGTAACTGCATTTGATTTCTATTTTGAAGATCGTC
GTGAAGTGCCGCCGCCATCGTCAGAGGGTGAGGCTTTTGTAGAAGTGCCGGCAAGCGTAGCTGCCAAGGTGCTTTTGCTC
AATGCCGTGGTTCAGGCTGGCGTAACCAACGCCGAGCTGGCCCGCATGATAGATACGCGCCCGCAAGAGATTACACGGGT
GTTTGATCTGCATCACTCGACCAAAATCGACACTATCCAGAAGGCGCTATCGGCGCTGGGCAAGCGGCTGGAACTGGCCG
CTGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References