115755

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4869801..4870485 Replicon chromosome
Accession NZ_CP034338
Organism Pseudomonas entomophila strain 1257

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag EJA05_RS22810 Protein ID WP_125860086.1
Coordinates 4869801..4870172 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag EJA05_RS22815 Protein ID WP_125860088.1
Coordinates 4870165..4870485 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJA05_RS22780 4865291..4866016 + 726 WP_110993430.1 LPS export ABC transporter ATP-binding protein -
EJA05_RS22785 4866201..4867694 + 1494 WP_125860080.1 RNA polymerase factor sigma-54 -
EJA05_RS22790 4867773..4868081 + 309 WP_110993432.1 ribosome-associated translation inhibitor RaiA -
EJA05_RS22795 4868094..4868558 + 465 WP_110993433.1 PTS IIA-like nitrogen regulatory protein PtsN -
EJA05_RS22800 4868561..4869415 + 855 WP_125860081.1 RNase adapter RapZ -
EJA05_RS22805 4869436..4869708 + 273 WP_125860083.1 HPr family phosphocarrier protein -
EJA05_RS22810 4869801..4870172 + 372 WP_125860086.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EJA05_RS22815 4870165..4870485 + 321 WP_125860088.1 helix-turn-helix domain-containing protein Antitoxin
EJA05_RS22820 4870489..4871382 - 894 WP_125861410.1 ZIP family metal transporter -
EJA05_RS22825 4871394..4872005 - 612 WP_125860090.1 superoxide dismutase -
EJA05_RS22830 4872007..4872468 - 462 WP_125860092.1 hypothetical protein -
EJA05_RS22835 4872494..4873870 - 1377 WP_125860094.1 class II fumarate hydratase -
EJA05_RS22840 4873863..4874264 - 402 WP_125860096.1 FagA protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13742.70 Da        Isoelectric Point: 9.9274

>T115755 WP_125860086.1 NZ_CP034338:4869801-4870172 [Pseudomonas entomophila]
MEAIKNVKRLFWVGSSRKDIQALPADVQDVFGFALYQAQEGGKHWQAKVLKGFSGGGVLEVVEDHHGDTYRAVYTISLVD
AVYVLHCFQKKSRSGIKTSRHDVDLIHARLKLAQAHSKGKTHD

Download         Length: 372 bp

>T115755 NZ_CP034338:4869801-4870172 [Pseudomonas entomophila]
ATGGAAGCGATCAAGAATGTCAAACGCCTGTTCTGGGTTGGTAGCTCCCGAAAGGATATCCAGGCACTCCCGGCTGATGT
CCAAGATGTGTTCGGTTTTGCTCTGTATCAGGCTCAGGAAGGCGGCAAGCACTGGCAGGCAAAGGTGCTTAAAGGGTTTT
CAGGCGGCGGCGTGCTCGAGGTGGTCGAAGACCATCACGGCGACACCTATCGTGCGGTCTACACCATCAGCCTGGTCGAC
GCGGTTTACGTGCTGCACTGTTTCCAGAAGAAATCCCGCAGCGGCATCAAAACCTCAAGGCATGACGTGGATTTGATTCA
TGCCCGCCTGAAACTGGCACAGGCTCACTCGAAGGGGAAAACACATGATTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11669.71 Da        Isoelectric Point: 8.2760

>AT115755 WP_125860088.1 NZ_CP034338:4870165-4870485 [Pseudomonas entomophila]
MIEIEEGTDNVYADLHLADASEMLVKACLASKICSIIKARQLTQLQAAELLGLSQPKVSALTRGKFRGISESKMIDCLAR
LGRDIQIVVKEAPKTRREGRVEVIFA

Download         Length: 321 bp

>AT115755 NZ_CP034338:4870165-4870485 [Pseudomonas entomophila]
ATGATTGAAATCGAAGAAGGCACAGACAACGTCTATGCCGACCTGCACCTTGCCGACGCCAGCGAGATGCTGGTCAAGGC
CTGCCTGGCCAGCAAGATCTGCAGCATCATCAAGGCACGCCAGCTCACTCAACTACAGGCCGCTGAGCTGCTCGGCCTGA
GCCAACCCAAGGTCTCCGCCCTGACCCGCGGCAAATTCCGTGGCATCAGCGAAAGCAAGATGATCGATTGCCTCGCCCGC
CTGGGCCGGGACATACAGATCGTGGTCAAGGAAGCCCCCAAGACCCGGCGCGAAGGCCGGGTGGAAGTGATTTTCGCCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References