Detailed information of TA system TA115753

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3883382..3883898
• Replicon: chromosome
• Accession: NZ_CP034338
• Organism: Pseudomonas entomophila strain 1257

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EJA05_RS18260
• Protein ID: WP_125859321.1
• Coordinates: 3883382..3883663 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EJA05_RS18265
• Protein ID: WP_125464712.1
• Coordinates: 3883653..3883898 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EJA05_RS18240	3878665..3879480	+	816	WP_125859317.1	protein phosphatase 2C domain-containing protein	-
EJA05_RS18245	3879617..3880978	+	1362	WP_125859318.1	hypothetical protein	-
EJA05_RS18250	3881140..3881712	+	573	WP_125859319.1	ComF family protein	-
EJA05_RS18255	3881803..3883140	-	1338	WP_125859320.1	OprD family porin	-
EJA05_RS18260	3883382..3883663	-	282	WP_125859321.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EJA05_RS18265	3883653..3883898	-	246	WP_125464712.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
EJA05_RS18270	3884108..3884569	+	462	WP_190306001.1	PaaI family thioesterase	-
EJA05_RS18275	3884690..3885013	+	324	WP_125859323.1	DUF2790 domain-containing protein	-
EJA05_RS18280	3885024..3885752	-	729	WP_125859324.1	hypothetical protein	-
EJA05_RS18285	3885870..3886616	-	747	WP_125859325.1	sulfite exporter TauE/SafE family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-77)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10759.69 Da
• Isoelectric Point: 10.9348

>T115753 WP_125859321.1 NZ_CP034338:c3883663-3883382 [Pseudomonas entomophila]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLRERLVLPRGPADALRDLPNHYKIKLKSSGYRLVYRVEDQRVVVLVVAVGK
REGAAAYRSALKR

Nucleotide

• Length: 282 bp

>T115753 NZ_CP034338:c3883663-3883382 [Pseudomonas entomophila]
ATGACCTATAAGCTCGAGTTTCTGCCCTCTGCGTTGAAGGAGTGGGAGAAACTTGGCCATACCGTGCGTGAGCAAGCCAA
GAAGAAACTGCGTGAGCGGCTGGTACTGCCCAGGGGGCCAGCGGACGCGCTGCGCGACTTGCCCAACCACTACAAGATCA
AACTCAAGTCCTCAGGTTATCGGCTGGTCTATCGGGTAGAGGATCAGCGAGTCGTTGTGCTGGTGGTGGCGGTAGGCAAG
CGCGAAGGCGCGGCGGCCTATCGCTCTGCTCTGAAGCGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8907.37 Da
• Isoelectric Point: 4.6982

>AT115753 WP_125464712.1 NZ_CP034338:c3883898-3883653 [Pseudomonas entomophila]
MQNIFADITVSVSELKKNPTAVMAGAQGQPVAVLNHNRVMGYMVPAELYEAMMEQLEDIELAQLVKARAHEKGVPVKLDD
L

Nucleotide

• Length: 246 bp

>AT115753 NZ_CP034338:c3883898-3883653 [Pseudomonas entomophila]
ATGCAGAACATCTTCGCCGACATCACCGTCAGCGTCTCGGAATTGAAGAAGAATCCCACGGCTGTCATGGCAGGTGCACA
GGGGCAGCCAGTGGCAGTGCTCAATCATAATCGCGTCATGGGCTACATGGTGCCCGCTGAACTCTATGAGGCGATGATGG
AGCAACTGGAAGACATCGAGCTGGCGCAATTGGTCAAGGCACGTGCGCACGAGAAGGGCGTGCCGGTGAAGCTGGATGAC
CTATAA