Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/UPF0150(antitoxin) |
| Location | 1267004..1267632 | Replicon | chromosome |
| Accession | NZ_CP034338 | ||
| Organism | Pseudomonas entomophila strain 1257 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | EJA05_RS05995 | Protein ID | WP_125857637.1 |
| Coordinates | 1267004..1267186 (+) | Length | 61 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | EJA05_RS06000 | Protein ID | WP_125857638.1 |
| Coordinates | 1267207..1267632 (+) | Length | 142 a.a. |
Genomic Context
Location: 1262856..1263950 (1095 bp)
Type: Others
Protein ID: WP_125462864.1
Type: Others
Protein ID: WP_125462864.1
Location: 1264729..1265295 (567 bp)
Type: Others
Protein ID: WP_003258001.1
Type: Others
Protein ID: WP_003258001.1
Location: 1265394..1265624 (231 bp)
Type: Others
Protein ID: WP_110995504.1
Type: Others
Protein ID: WP_110995504.1
Location: 1267004..1267186 (183 bp)
Type: Toxin
Protein ID: WP_125857637.1
Type: Toxin
Protein ID: WP_125857637.1
Location: 1267207..1267632 (426 bp)
Type: Antitoxin
Protein ID: WP_125857638.1
Type: Antitoxin
Protein ID: WP_125857638.1
Location: 1264179..1264388 (210 bp)
Type: Others
Protein ID: WP_016488765.1
Type: Others
Protein ID: WP_016488765.1
Location: 1265656..1266771 (1116 bp)
Type: Others
Protein ID: WP_125857636.1
Type: Others
Protein ID: WP_125857636.1
Location: 1267687..1270122 (2436 bp)
Type: Others
Protein ID: WP_125857639.1
Type: Others
Protein ID: WP_125857639.1
Location: 1270311..1270514 (204 bp)
Type: Others
Protein ID: WP_012313055.1
Type: Others
Protein ID: WP_012313055.1
Location: 1270522..1270998 (477 bp)
Type: Others
Protein ID: WP_125857640.1
Type: Others
Protein ID: WP_125857640.1
Location: 1271001..1271477 (477 bp)
Type: Others
Protein ID: WP_125857641.1
Type: Others
Protein ID: WP_125857641.1
Location: 1271482..1271976 (495 bp)
Type: Others
Protein ID: WP_125462869.1
Type: Others
Protein ID: WP_125462869.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EJA05_RS05970 | 1262856..1263950 | + | 1095 | WP_125462864.1 | iron-sulfur cluster carrier protein ApbC | - |
| EJA05_RS05975 | 1264179..1264388 | - | 210 | WP_016488765.1 | cold-shock protein | - |
| EJA05_RS05980 | 1264729..1265295 | + | 567 | WP_003258001.1 | dCTP deaminase | - |
| EJA05_RS05985 | 1265394..1265624 | + | 231 | WP_110995504.1 | hypothetical protein | - |
| EJA05_RS05990 | 1265656..1266771 | - | 1116 | WP_125857636.1 | succinylglutamate desuccinylase/aspartoacylase family protein | - |
| EJA05_RS05995 | 1267004..1267186 | + | 183 | WP_125857637.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| EJA05_RS06000 | 1267207..1267632 | + | 426 | WP_125857638.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| EJA05_RS06005 | 1267687..1270122 | - | 2436 | WP_125857639.1 | penicillin acylase family protein | - |
| EJA05_RS06010 | 1270311..1270514 | - | 204 | WP_012313055.1 | SEC-C domain-containing protein | - |
| EJA05_RS06015 | 1270522..1270998 | - | 477 | WP_125857640.1 | LEA type 2 family protein | - |
| EJA05_RS06020 | 1271001..1271477 | - | 477 | WP_125857641.1 | YchJ family protein | - |
| EJA05_RS06025 | 1271482..1271976 | - | 495 | WP_125462869.1 | hypothetical protein | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6848.00 Da Isoelectric Point: 10.8431
>T115752 WP_125857637.1 NZ_CP034338:1267004-1267186 [Pseudomonas entomophila]
MKYSEFRRWLRAQGATFVPAKGSHFKVYLGKRQTIFPDHGAKEIGEGLRKKILKDLGLGD
MKYSEFRRWLRAQGATFVPAKGSHFKVYLGKRQTIFPDHGAKEIGEGLRKKILKDLGLGD
Download Length: 183 bp
>T115752 NZ_CP034338:1267004-1267186 [Pseudomonas entomophila]
ATGAAATACAGCGAATTCCGTCGGTGGCTGCGTGCTCAAGGCGCCACGTTCGTTCCTGCCAAAGGCAGCCATTTCAAGGT
TTACCTCGGCAAACGACAGACGATCTTCCCCGACCATGGCGCCAAGGAAATTGGCGAAGGGCTCAGGAAAAAGATCCTCA
AAGACCTTGGGCTAGGCGATTGA
ATGAAATACAGCGAATTCCGTCGGTGGCTGCGTGCTCAAGGCGCCACGTTCGTTCCTGCCAAAGGCAGCCATTTCAAGGT
TTACCTCGGCAAACGACAGACGATCTTCCCCGACCATGGCGCCAAGGAAATTGGCGAAGGGCTCAGGAAAAAGATCCTCA
AAGACCTTGGGCTAGGCGATTGA
Antitoxin
Download Length: 142 a.a. Molecular weight: 15408.81 Da Isoelectric Point: 5.9738
>AT115752 WP_125857638.1 NZ_CP034338:1267207-1267632 [Pseudomonas entomophila]
MNFDYPVIVHCEAGSFWISCPDIPEMASAGGTMDEALFDAVDALESALSLYVDRRDAIPLPSPHGCDQAVVRLPALTAAK
AALWNTMIAQKVTKTELARRLGVNRPQVDRLVNLLHRSKIEQVEHALHVLGQRIELAVVAA
MNFDYPVIVHCEAGSFWISCPDIPEMASAGGTMDEALFDAVDALESALSLYVDRRDAIPLPSPHGCDQAVVRLPALTAAK
AALWNTMIAQKVTKTELARRLGVNRPQVDRLVNLLHRSKIEQVEHALHVLGQRIELAVVAA
Download Length: 426 bp
>AT115752 NZ_CP034338:1267207-1267632 [Pseudomonas entomophila]
ATGAATTTTGATTATCCGGTGATCGTGCATTGTGAAGCAGGCAGCTTCTGGATCAGCTGTCCGGATATTCCAGAAATGGC
CAGTGCGGGCGGCACGATGGATGAGGCGTTGTTCGATGCTGTCGATGCCTTGGAGTCGGCGCTTTCGTTATACGTGGATC
GGCGTGACGCGATTCCACTGCCTTCGCCACACGGATGCGATCAGGCGGTGGTCAGGTTGCCTGCGTTGACCGCCGCCAAG
GCCGCGCTGTGGAACACCATGATTGCGCAGAAAGTGACCAAGACCGAACTGGCTCGGCGACTTGGCGTCAATCGGCCACA
AGTGGATCGTCTGGTCAACCTGTTGCATCGCTCGAAGATCGAGCAGGTAGAGCACGCCTTGCATGTGTTGGGCCAGCGTA
TCGAATTGGCAGTGGTCGCTGCTTGA
ATGAATTTTGATTATCCGGTGATCGTGCATTGTGAAGCAGGCAGCTTCTGGATCAGCTGTCCGGATATTCCAGAAATGGC
CAGTGCGGGCGGCACGATGGATGAGGCGTTGTTCGATGCTGTCGATGCCTTGGAGTCGGCGCTTTCGTTATACGTGGATC
GGCGTGACGCGATTCCACTGCCTTCGCCACACGGATGCGATCAGGCGGTGGTCAGGTTGCCTGCGTTGACCGCCGCCAAG
GCCGCGCTGTGGAACACCATGATTGCGCAGAAAGTGACCAAGACCGAACTGGCTCGGCGACTTGGCGTCAATCGGCCACA
AGTGGATCGTCTGGTCAACCTGTTGCATCGCTCGAAGATCGAGCAGGTAGAGCACGCCTTGCATGTGTTGGGCCAGCGTA
TCGAATTGGCAGTGGTCGCTGCTTGA