Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 927446..927965 Replicon chromosome
Accession NZ_CP034338
Organism Pseudomonas entomophila strain 1257

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EJA05_RS04420 Protein ID WP_125857463.1
Coordinates 927446..927736 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EJA05_RS04425 Protein ID WP_125462610.1
Coordinates 927726..927965 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJA05_RS04395 923855..924076 + 222 WP_125857459.1 hypothetical protein -
EJA05_RS04400 924146..924739 - 594 WP_125857460.1 hypothetical protein -
EJA05_RS04405 924942..926009 + 1068 WP_125857461.1 ImmA/IrrE family metallo-endopeptidase -
EJA05_RS04410 925990..926475 + 486 Protein_831 PIN domain-containing protein -
EJA05_RS04415 926553..927326 + 774 WP_125857462.1 carbon-nitrogen hydrolase family protein -
EJA05_RS04420 927446..927736 - 291 WP_125857463.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EJA05_RS04425 927726..927965 - 240 WP_125462610.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EJA05_RS04430 928069..929556 - 1488 WP_125857464.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
EJA05_RS04435 929838..931088 - 1251 WP_125857465.1 IS256 family transposase -
EJA05_RS04440 931302..932339 + 1038 Protein_837 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
EJA05_RS04445 932428..932952 + 525 WP_125857466.1 histidine phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 904542..931088 26546
- flank IS/Tn - - 929838..931088 1250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11443.25 Da        Isoelectric Point: 10.0984

>T115750 WP_125857463.1 NZ_CP034338:c927736-927446 [Pseudomonas entomophila]
MTYNLEFDARALKEWQKLGDTLRQQFKKKLATILLNPRVEANRLHGFPDCYKIKLRSSGYRLVYQVIDHEVVVFVISVDK
RERDQVYRKAAERLSE

Download         Length: 291 bp

>T115750 NZ_CP034338:c927736-927446 [Pseudomonas entomophila]
ATGACCTATAACCTCGAATTCGATGCGCGCGCACTTAAGGAATGGCAGAAACTCGGCGACACCCTTCGACAACAGTTCAA
GAAGAAACTGGCAACGATATTGCTCAATCCAAGGGTTGAAGCGAACCGCCTGCACGGCTTCCCGGACTGCTACAAGATCA
AGTTGCGAAGCAGTGGCTATCGATTGGTCTACCAAGTCATCGACCATGAGGTCGTAGTGTTCGTGATCAGCGTGGATAAA
CGGGAGCGAGACCAGGTTTACCGCAAGGCGGCGGAGCGATTGAGCGAGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8992.41 Da        Isoelectric Point: 4.8011

>AT115750 WP_125462610.1 NZ_CP034338:c927965-927726 [Pseudomonas entomophila]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEDDEALLATVRERLAAPQRVKVTLDDL

Download         Length: 240 bp

>AT115750 NZ_CP034338:c927965-927726 [Pseudomonas entomophila]
ATGGCGTCCATCAATGTGCGGATCGACGACGACCTCAAGGTGCGTGCCTACCGTGAACTGGAAAAGCTGGGCGTAACCCC
TTCCGAACTGATGCGCCAGGCGTTGCAGTATGTCGCTGAGCGTGGGCAACTGCCTTTCAAGCCTGTGTTGTTGACCGAAG
ACGACGAAGCCTTGCTCGCCACCGTGCGCGAACGTCTGGCCGCCCCTCAGAGGGTGAAGGTAACGCTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References