115746

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4518211..4518856 Replicon chromosome
Accession NZ_CP034337
Organism Pseudomonas entomophila strain 2014

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag EI693_RS21010 Protein ID WP_125465343.1
Coordinates 4518211..4518543 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag EI693_RS21015 Protein ID WP_125465344.1
Coordinates 4518536..4518856 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI693_RS20980 4513668..4514393 + 726 WP_110993430.1 LPS export ABC transporter ATP-binding protein -
EI693_RS20985 4514578..4516071 + 1494 WP_125465341.1 RNA polymerase factor sigma-54 -
EI693_RS20990 4516150..4516458 + 309 WP_110993432.1 ribosome-associated translation inhibitor RaiA -
EI693_RS20995 4516471..4516935 + 465 WP_110993433.1 PTS IIA-like nitrogen regulatory protein PtsN -
EI693_RS21000 4516938..4517792 + 855 WP_125465342.1 RNase adapter RapZ -
EI693_RS21005 4517813..4518085 + 273 WP_110993435.1 HPr family phosphocarrier protein -
EI693_RS21010 4518211..4518543 + 333 WP_125465343.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EI693_RS21015 4518536..4518856 + 321 WP_125465344.1 helix-turn-helix domain-containing protein Antitoxin
EI693_RS21020 4518860..4519753 - 894 WP_125466243.1 ZIP family metal transporter -
EI693_RS21025 4519765..4520376 - 612 WP_125465345.1 superoxide dismutase -
EI693_RS21030 4520378..4520839 - 462 WP_125465346.1 hypothetical protein -
EI693_RS21035 4520865..4522241 - 1377 WP_110993441.1 class II fumarate hydratase -
EI693_RS21040 4522234..4522635 - 402 WP_125465347.1 FagA protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-98)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12137.69 Da        Isoelectric Point: 8.8489

>T115746 WP_125465343.1 NZ_CP034337:4518211-4518543 [Pseudomonas entomophila]
MGWKLSEGYPDTPGQDVFGFALYQAQEGGKHWQAKVLKGFSGGGVLEVVEDHHGDTYRAVYTVSLADAVYVLHCFQKKSR
SGIKTSKHDVDLIHARLKLAQAHSKGKTHD

Download         Length: 333 bp

>T115746 NZ_CP034337:4518211-4518543 [Pseudomonas entomophila]
CTGGGTTGGAAGCTCTCGGAAGGATATCCAGACACTCCCGGCCAGGATGTATTCGGTTTTGCTCTGTATCAGGCCCAGGA
AGGCGGCAAGCATTGGCAGGCAAAGGTGCTCAAAGGGTTTTCAGGGGGCGGTGTGCTCGAGGTGGTCGAAGACCATCACG
GCGACACCTATCGTGCGGTCTACACCGTCAGCCTGGCCGACGCGGTTTACGTGCTGCACTGTTTCCAGAAGAAATCCCGC
AGCGGCATCAAAACTTCAAAGCATGACGTGGATTTGATCCATGCCCGCCTGAAACTGGCACAGGCTCACTCGAAGGGGAA
AACACATGATTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11722.75 Da        Isoelectric Point: 9.2305

>AT115746 WP_125465344.1 NZ_CP034337:4518536-4518856 [Pseudomonas entomophila]
MIEIEEGTDNVYADLHLADASEMLVKARLASKICSIIKARQLTQLQAAELLGLSQPKVSALTRGKFRGISESKMIDCLAR
LGRDIQIVVKEAPKTRREGRVEVIFA

Download         Length: 321 bp

>AT115746 NZ_CP034337:4518536-4518856 [Pseudomonas entomophila]
ATGATTGAAATCGAAGAAGGCACAGACAACGTCTATGCCGACCTGCACCTTGCCGACGCCAGCGAGATGCTGGTCAAGGC
CCGCCTGGCCAGCAAGATCTGCAGCATCATCAAGGCACGCCAGCTCACTCAACTGCAGGCCGCCGAGTTGCTCGGCCTGA
GCCAACCCAAGGTCTCCGCCCTGACCCGCGGCAAATTCCGTGGCATCAGCGAAAGCAAGATGATCGATTGCCTCGCCCGC
CTGGGCCGAGACATACAGATCGTGGTCAAGGAAGCACCCAAGACCCGGCGCGAAGGCCGGGTGGAAGTGATTTTCGCCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References