Detailed information of TA system TA115744

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3626314..3626830
• Replicon: chromosome
• Accession: NZ_CP034337
• Organism: Pseudomonas entomophila strain 2014

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EI693_RS16900
• Protein ID: WP_125464711.1
• Coordinates: 3626314..3626595 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EI693_RS16905
• Protein ID: WP_125464712.1
• Coordinates: 3626585..3626830 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EI693_RS16885	3621980..3622552	+	573	WP_125464708.1	ComF family protein	-
EI693_RS16890	3622707..3624614	+	1908	WP_125464709.1	HAD-IA family hydrolase	-
EI693_RS16895	3624737..3626074	-	1338	WP_125464710.1	OprD family porin	-
EI693_RS16900	3626314..3626595	-	282	WP_125464711.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EI693_RS16905	3626585..3626830	-	246	WP_125464712.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
EI693_RS16910	3627039..3627500	+	462	WP_189654481.1	PaaI family thioesterase	-
EI693_RS16915	3627621..3627944	+	324	WP_125464714.1	DUF2790 domain-containing protein	-
EI693_RS16920	3627955..3628683	-	729	WP_125464715.1	hypothetical protein	-
EI693_RS16925	3628801..3629547	-	747	WP_125464716.1	sulfite exporter TauE/SafE family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3626314..3651192	24878

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-77)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10801.77 Da
• Isoelectric Point: 10.9348

>T115744 WP_125464711.1 NZ_CP034337:c3626595-3626314 [Pseudomonas entomophila]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLRERLVLPRVPADALRDLPNHYKIKLKSSGYRLVYRVEDQRVVVLVVAVGK
REGAAAYRSALKR

Nucleotide

• Length: 282 bp

>T115744 NZ_CP034337:c3626595-3626314 [Pseudomonas entomophila]
ATGACCTATAAGCTCGAGTTTCTGCCCTCTGCGTTGAAGGAGTGGGAGAAACTTGGCCATACCGTGCGTGAGCAAGCCAA
GAAGAAACTGCGTGAGCGGCTGGTACTGCCCAGGGTGCCAGCGGACGCGCTGCGCGACTTGCCCAACCACTACAAGATCA
AACTCAAGTCCTCAGGTTATCGACTGGTCTATCGGGTAGAGGATCAGCGAGTCGTTGTGCTGGTGGTGGCGGTAGGCAAG
CGCGAAGGCGCGGCGGCCTATCGCTCTGCTCTGAAGCGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8907.37 Da
• Isoelectric Point: 4.6982

>AT115744 WP_125464712.1 NZ_CP034337:c3626830-3626585 [Pseudomonas entomophila]
MQNIFADITVSVSELKKNPTAVMAGAQGQPVAVLNHNRVMGYMVPAELYEAMMEQLEDIELAQLVKARAHEKGVPVKLDD
L

Nucleotide

• Length: 246 bp

>AT115744 NZ_CP034337:c3626830-3626585 [Pseudomonas entomophila]
ATGCAGAACATCTTCGCCGACATCACCGTCAGCGTTTCGGAATTGAAGAAGAATCCCACGGCTGTCATGGCAGGTGCACA
GGGGCAGCCAGTGGCAGTGCTCAATCATAATCGCGTCATGGGCTACATGGTGCCCGCTGAACTCTATGAGGCGATGATGG
AGCAACTGGAAGACATCGAGCTGGCGCAATTGGTCAAGGCACGTGCGCACGAGAAGGGCGTGCCGGTGAAGCTGGATGAC
CTATAA