Detailed information of TA system TA115742

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 856259..856778
• Replicon: chromosome
• Accession: NZ_CP034337
• Organism: Pseudomonas entomophila strain 2014

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EI693_RS04145
• Protein ID: WP_125462609.1
• Coordinates: 856259..856549 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EI693_RS04150
• Protein ID: WP_125462610.1
• Coordinates: 856539..856778 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EI693_RS04120	851995..853737	+	1743	WP_125462605.1	ATP-binding protein	-
EI693_RS04130	854345..854566	+	222	WP_125462606.1	hypothetical protein	-
EI693_RS04135	854636..855235	-	600	WP_125462607.1	hypothetical protein	-
EI693_RS04140	855366..856139	+	774	WP_125462608.1	carbon-nitrogen hydrolase family protein	-
EI693_RS04145	856259..856549	-	291	WP_125462609.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EI693_RS04150	856539..856778	-	240	WP_125462610.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
EI693_RS04155	856881..858368	-	1488	WP_125462611.1	methylenetetrahydrofolate reductase C-terminal domain-containing protein	-
EI693_RS04160	858732..859769	+	1038	Protein_778	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	-
EI693_RS04165	859858..860382	+	525	WP_125462612.1	histidine phosphatase family protein	-
EI693_RS04170	860532..861488	-	957	WP_125462613.1	arsenic resistance protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-64)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11385.17 Da
• Isoelectric Point: 10.0984

>T115742 WP_125462609.1 NZ_CP034337:c856549-856259 [Pseudomonas entomophila]
MTYNLEFDARALKEWQKLGDTLRQQFKKKLATVLLNPRVEANRLHGFPDCYKIKLRSSGYRLVYQVIDHEVVVFVVSVDK
RERDQVYRKAAERLGE

Nucleotide

• Length: 291 bp

>T115742 NZ_CP034337:c856549-856259 [Pseudomonas entomophila]
ATGACCTATAACCTCGAATTCGATGCACGCGCACTTAAGGAATGGCAGAAACTCGGCGACACCCTTCGCCAACAGTTCAA
GAAGAAACTGGCAACGGTATTGCTCAATCCAAGGGTTGAAGCGAACCGCCTGCACGGCTTCCCGGACTGCTACAAGATCA
AGTTGCGAAGCAGTGGCTATCGATTGGTCTACCAAGTCATCGACCATGAGGTCGTAGTGTTCGTGGTCAGCGTGGATAAA
CGGGAGCGAGACCAGGTTTACCGCAAGGCGGCCGAGCGATTGGGCGAGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8992.41 Da
• Isoelectric Point: 4.8011

>AT115742 WP_125462610.1 NZ_CP034337:c856778-856539 [Pseudomonas entomophila]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEDDEALLATVRERLAAPQRVKVTLDDL

Nucleotide

• Length: 240 bp

>AT115742 NZ_CP034337:c856778-856539 [Pseudomonas entomophila]
ATGGCGTCCATCAATGTGCGTATCGACGACGACCTCAAGGTGCGTGCCTACCGTGAACTGGAAAAGCTGGGCGTAACCCC
TTCCGAACTGATGCGCCAGGCGTTGCAGTATGTCGCTGAACGTGGGCAACTGCCTTTCAAGCCTGTGTTGTTGACCGAAG
ACGACGAAGCCTTGCTCGCCACCGTGCGCGAACGTCTGGCCGCCCCTCAGAGGGTGAAGGTAACGCTGGATGACCTATAA