Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 856259..856778 Replicon chromosome
Accession NZ_CP034337
Organism Pseudomonas entomophila strain 2014

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EI693_RS04145 Protein ID WP_125462609.1
Coordinates 856259..856549 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EI693_RS04150 Protein ID WP_125462610.1
Coordinates 856539..856778 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI693_RS04120 851995..853737 + 1743 WP_125462605.1 ATP-binding protein -
EI693_RS04130 854345..854566 + 222 WP_125462606.1 hypothetical protein -
EI693_RS04135 854636..855235 - 600 WP_125462607.1 hypothetical protein -
EI693_RS04140 855366..856139 + 774 WP_125462608.1 carbon-nitrogen hydrolase family protein -
EI693_RS04145 856259..856549 - 291 WP_125462609.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EI693_RS04150 856539..856778 - 240 WP_125462610.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EI693_RS04155 856881..858368 - 1488 WP_125462611.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
EI693_RS04160 858732..859769 + 1038 Protein_778 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
EI693_RS04165 859858..860382 + 525 WP_125462612.1 histidine phosphatase family protein -
EI693_RS04170 860532..861488 - 957 WP_125462613.1 arsenic resistance protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11385.17 Da        Isoelectric Point: 10.0984

>T115742 WP_125462609.1 NZ_CP034337:c856549-856259 [Pseudomonas entomophila]
MTYNLEFDARALKEWQKLGDTLRQQFKKKLATVLLNPRVEANRLHGFPDCYKIKLRSSGYRLVYQVIDHEVVVFVVSVDK
RERDQVYRKAAERLGE

Download         Length: 291 bp

>T115742 NZ_CP034337:c856549-856259 [Pseudomonas entomophila]
ATGACCTATAACCTCGAATTCGATGCACGCGCACTTAAGGAATGGCAGAAACTCGGCGACACCCTTCGCCAACAGTTCAA
GAAGAAACTGGCAACGGTATTGCTCAATCCAAGGGTTGAAGCGAACCGCCTGCACGGCTTCCCGGACTGCTACAAGATCA
AGTTGCGAAGCAGTGGCTATCGATTGGTCTACCAAGTCATCGACCATGAGGTCGTAGTGTTCGTGGTCAGCGTGGATAAA
CGGGAGCGAGACCAGGTTTACCGCAAGGCGGCCGAGCGATTGGGCGAGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8992.41 Da        Isoelectric Point: 4.8011

>AT115742 WP_125462610.1 NZ_CP034337:c856778-856539 [Pseudomonas entomophila]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEDDEALLATVRERLAAPQRVKVTLDDL

Download         Length: 240 bp

>AT115742 NZ_CP034337:c856778-856539 [Pseudomonas entomophila]
ATGGCGTCCATCAATGTGCGTATCGACGACGACCTCAAGGTGCGTGCCTACCGTGAACTGGAAAAGCTGGGCGTAACCCC
TTCCGAACTGATGCGCCAGGCGTTGCAGTATGTCGCTGAACGTGGGCAACTGCCTTTCAAGCCTGTGTTGTTGACCGAAG
ACGACGAAGCCTTGCTCGCCACCGTGCGCGAACGTCTGGCCGCCCCTCAGAGGGTGAAGGTAACGCTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References