Detailed information of TA system TA115726

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1669526..1670009
• Replicon: chromosome
• Accession: NZ_CP034328
• Organism: Tabrizicola piscis strain K13M18

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EI545_RS08040
• Protein ID: WP_125324993.1
• Coordinates: 1669746..1670009 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EI545_RS08035
• Protein ID: WP_125327294.1
• Coordinates: 1669526..1669741 (-)
• Length: 72 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EI545_RS07975	1664833..1665021	-	189	WP_125324982.1	50S ribosomal protein L30	-
EI545_RS07980	1665024..1665590	-	567	WP_125324983.1	30S ribosomal protein S5	-
EI545_RS07985	1665715..1666074	-	360	WP_125324984.1	50S ribosomal protein L18	-
EI545_RS07990	1666086..1666619	-	534	WP_125324985.1	50S ribosomal protein L6	-
EI545_RS07995	1666631..1667029	-	399	WP_125324986.1	30S ribosomal protein S8	-
EI545_RS08000	1667042..1667347	-	306	WP_125324987.1	30S ribosomal protein S14	-
EI545_RS08005	1667365..1667925	-	561	WP_125324988.1	50S ribosomal protein L5	-
EI545_RS08010	1667925..1668230	-	306	WP_125324989.1	50S ribosomal protein L24	-
EI545_RS08015	1668230..1668598	-	369	WP_091302592.1	50S ribosomal protein L14	-
EI545_RS08020	1668657..1668896	-	240	WP_125324990.1	30S ribosomal protein S17	-
EI545_RS08025	1668908..1669108	-	201	WP_125324991.1	50S ribosomal protein L29	-
EI545_RS08035	1669526..1669741	-	216	WP_125327294.1	CopG family transcriptional regulator	Antitoxin
EI545_RS08040	1669746..1670009	-	264	WP_125324993.1	BrnT family toxin	Toxin
EI545_RS08045	1670052..1670675	-	624	WP_125324994.1	hypothetical protein	-
EI545_RS08050	1670902..1671315	-	414	WP_125324995.1	50S ribosomal protein L16	-
EI545_RS08055	1671329..1672045	-	717	WP_125324996.1	30S ribosomal protein S3	-
EI545_RS08060	1672045..1672434	-	390	WP_125324997.1	50S ribosomal protein L22	-
EI545_RS08065	1672438..1672716	-	279	WP_125324998.1	30S ribosomal protein S19	-
EI545_RS08070	1672720..1673559	-	840	WP_125324999.1	50S ribosomal protein L2	-
EI545_RS08075	1673777..1674766	-	990	WP_125325000.1	DUF4238 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

• CopG antitoxin (6-69)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9749.08 Da
• Isoelectric Point: 5.1116

>T115726 WP_125324993.1 NZ_CP034328:c1670009-1669746 [Tabrizicola piscis]
MEFEFDPDKSAANKVKHGIDFVEAQALWQDDGLADAPVVSDGEPRFLVIGRIDGKHWTAVCTLRGEVVRIISVRRARKTE
VMFYDGA

Nucleotide

• Length: 264 bp

>T115726 NZ_CP034328:c1670009-1669746 [Tabrizicola piscis]
ATGGAGTTCGAGTTCGACCCAGACAAGAGTGCCGCCAACAAAGTCAAGCACGGCATCGACTTCGTCGAGGCTCAGGCACT
TTGGCAGGATGACGGGCTGGCCGATGCTCCGGTCGTATCGGATGGCGAGCCGCGCTTCCTTGTGATCGGTCGGATCGACG
GCAAGCACTGGACGGCGGTCTGCACTCTTCGCGGTGAGGTGGTGCGGATCATCTCGGTCCGGAGGGCGCGAAAAACGGAG
GTGATGTTCTATGACGGCGCGTGA

Antitoxin

Protein

• Length: 72 a.a.
• Molecular weight: 8288.34 Da
• Isoelectric Point: 4.7571

>AT115726 WP_125327294.1 NZ_CP034328:c1669741-1669526 [Tabrizicola piscis]
ITTEQFDEMFDNGEDVSAYVDWSKARRPNQEARRVNVDFPAWMVRDLDKEAGRLGVTRQSLIKMWIAEKLG

Nucleotide

• Length: 216 bp

>AT115726 NZ_CP034328:c1669741-1669526 [Tabrizicola piscis]
ATTACGACCGAACAGTTCGACGAAATGTTCGACAATGGCGAAGATGTCAGCGCTTACGTCGACTGGTCCAAAGCCCGCCG
CCCCAATCAGGAGGCGCGGCGCGTGAACGTGGACTTTCCGGCTTGGATGGTCCGCGACCTCGACAAGGAGGCCGGGCGTC
TGGGAGTGACGCGGCAGTCGCTGATCAAGATGTGGATCGCGGAGAAGTTGGGGTAG