Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1873428..1873573 Replicon chromosome
Accession NZ_CP034321
Organism Klebsiella pneumoniae strain 33

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1873464..1873566 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1873428..1873573 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJB01_RS09265 1868558..1870618 + 2061 WP_047694778.1 oligopeptidase B -
EJB01_RS09270 1870622..1871281 - 660 WP_002911407.1 exodeoxyribonuclease X -
EJB01_RS09275 1871360..1871590 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EJB01_RS09280 1871703..1872077 + 375 WP_023285314.1 CopC domain-containing protein YobA -
EJB01_RS09285 1872081..1872950 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
EJB01_RS09290 1872967..1873305 + 339 WP_002911404.1 YebY family protein -
- 1873428..1873573 - 146 - - Antitoxin
- 1873464..1873566 + 103 - - Toxin
EJB01_RS09295 1873941..1874084 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EJB01_RS09300 1874189..1875157 - 969 WP_004151446.1 VirK/YbjX family protein -
EJB01_RS09305 1875314..1875967 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
EJB01_RS09310 1875964..1876155 - 192 WP_002911395.1 YebW family protein -
EJB01_RS09315 1876253..1876492 - 240 WP_002911393.1 YebV family protein -
EJB01_RS09320 1876608..1878041 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115710 NZ_CP034321:1873464-1873566 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115710 NZ_CP034321:c1873573-1873428 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References