Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1318682..1319247 Replicon chromosome
Accession NZ_CP034305
Organism Vibrio parahaemolyticus strain 20151116002-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EHC68_RS06490 Protein ID WP_031856567.1
Coordinates 1318960..1319247 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EHC68_RS06485 Protein ID WP_031856568.1
Coordinates 1318682..1318963 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHC68_RS06445 1313806..1314393 + 588 WP_031856425.1 HD domain-containing protein -
EHC68_RS06450 1314407..1314880 + 474 WP_005458833.1 DUF2947 domain-containing protein -
EHC68_RS06455 1314931..1315893 - 963 WP_023623891.1 integron integrase -
EHC68_RS06460 1316150..1316650 + 501 WP_031856426.1 hypothetical protein -
EHC68_RS06465 1316689..1316781 + 93 WP_079880850.1 DUF3265 domain-containing protein -
EHC68_RS06470 1316809..1317339 + 531 WP_050505289.1 hypothetical protein -
EHC68_RS06475 1317502..1317825 - 324 WP_168192476.1 hypothetical protein -
EHC68_RS06480 1317912..1318043 + 132 WP_004418121.1 DUF3265 domain-containing protein -
EHC68_RS06485 1318682..1318963 + 282 WP_031856568.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EHC68_RS06490 1318960..1319247 + 288 WP_031856567.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EHC68_RS06495 1319394..1319666 + 273 WP_031856534.1 nicotinamide mononucleotide transporter -
EHC68_RS06500 1319698..1319787 + 90 WP_085626715.1 DUF3265 domain-containing protein -
EHC68_RS26680 1319979..1320335 + 357 Protein_1134 DUF3265 domain-containing protein -
EHC68_RS06510 1320363..1320713 + 351 WP_025502458.1 hypothetical protein -
EHC68_RS06515 1320710..1320832 + 123 WP_071652165.1 DUF3265 domain-containing protein -
EHC68_RS06520 1321192..1321320 + 129 WP_108744602.1 DUF3265 domain-containing protein -
EHC68_RS06525 1321603..1321728 + 126 WP_085576728.1 DUF3265 domain-containing protein -
EHC68_RS06535 1322860..1323660 + 801 WP_043037961.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1314407..1445556 131149
- inside Integron - - 1314931..1439037 124106


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10986.63 Da        Isoelectric Point: 4.6104

>T115702 WP_031856567.1 NZ_CP034305:1318960-1319247 [Vibrio parahaemolyticus]
MKVVWSPLALQKLGDAAEFISLDNPAAAENWINEVFDKTELLGSMPEMGRFVPEMPNTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQMLSEDDL

Download         Length: 288 bp

>T115702 NZ_CP034305:1318960-1319247 [Vibrio parahaemolyticus]
ATGAAAGTAGTTTGGTCTCCACTAGCGCTTCAGAAGCTAGGTGATGCAGCGGAATTTATTTCTTTGGATAATCCAGCTGC
AGCAGAAAACTGGATAAACGAAGTTTTTGACAAAACTGAACTACTTGGAAGTATGCCTGAAATGGGGCGCTTTGTTCCTG
AAATGCCCAATACTAACTATCGTGAAATCATTTTTGGTCACTATCGTATTATCTATAGCTTAAGCCATGAAATCCGAGTA
CTGACAGTTCGTAATTGCCGTCAAATGTTGTCGGAAGATGACCTGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10428.93 Da        Isoelectric Point: 5.8650

>AT115702 WP_031856568.1 NZ_CP034305:1318682-1318963 [Vibrio parahaemolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGISN
DDARSQVLGRIKK

Download         Length: 282 bp

>AT115702 NZ_CP034305:1318682-1318963 [Vibrio parahaemolyticus]
ATGAGCCGTATTCATTTCGATCAAGATATTCAGCCGTTATCTGAATTTCGCGCAGGTGTAGCTTCTTACATCAAACAAAT
CAACGAGACTCGCCGTCCATTGGTTATCACACAGCGTGGTAAAGGTGTAGCTGTTGTTCTCGATGTTGCAGAGTATGAAG
CAATGCAAGAGAAGATCGAGTTACTGGAAGAAATGCGCACAGCTGAAGCTCAATTAGCTTCAGGCCTTGGTATTTCAAAT
GATGATGCTCGTTCTCAAGTACTGGGGCGCATTAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References