Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 137938..139625 Replicon chromosome
Accession NZ_CP034294
Organism Vibrio parahaemolyticus strain 20140829008-1

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag EHC66_RS00745 Protein ID WP_005378672.1
Coordinates 138402..139625 (+) Length 408 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag EHC66_RS00740 Protein ID WP_005378671.1
Coordinates 137938..138405 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHC66_RS00710 133138..133359 - 222 WP_005378664.1 AlpA family transcriptional regulator -
EHC66_RS00715 133437..134426 + 990 WP_159408067.1 50S ribosome-binding GTPase -
EHC66_RS00720 134537..134983 + 447 WP_005378667.1 hypothetical protein -
EHC66_RS00725 135024..135668 - 645 WP_005378668.1 inovirus Gp2 family protein -
EHC66_RS00730 135835..136959 - 1125 WP_031779007.1 hypothetical protein -
EHC66_RS00735 137014..137685 + 672 WP_005378670.1 hypothetical protein -
EHC66_RS00740 137938..138405 + 468 WP_005378671.1 DUF4065 domain-containing protein Antitoxin
EHC66_RS00745 138402..139625 + 1224 WP_005378672.1 RelA/SpoT domain-containing protein Toxin
EHC66_RS00750 139817..140926 - 1110 WP_025610459.1 tRNA (uridine(54)-C5)-methyltransferase TrmA -
EHC66_RS00755 141370..143244 + 1875 WP_140104106.1 TonB-dependent receptor -
EHC66_RS00760 143323..144006 + 684 WP_140104107.1 adenine nucleotide alpha hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(111-228)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-123)


Sequences

Toxin        


Download         Length: 408 a.a.        Molecular weight: 45878.65 Da        Isoelectric Point: 5.5472

>T115691 WP_005378672.1 NZ_CP034294:138402-139625 [Vibrio parahaemolyticus]
VSNKENSVVSFYIDDTPTAEQASKTFQDDYELDFQDFIERTVNESAAEDFSYSNNGVKKAGRRLRKREGDLKSATATIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLETIVDKLQRKSLDGETANATCVTNMNDIGGCRAIFPDLISLEKV
KSQLQLTVEKVGRVRIKDIDDYITSPKPNDCGYRSLHVIYRYDHASGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSSNEGKSSLQVQWEELLSIMSQYIADAEGAIELSDIDKANFSKRLVVLDREINALNRLSSFKILSEKVNSYCDSSI
EHVLLVINETSRELIFSEEFENYSQAISVYNAAEKVTRSYSRATSRLNTLLISTKNMGQLSEAYPNYLGDCASFITLLED
AMLSGES

Download         Length: 1224 bp

>T115691 NZ_CP034294:138402-139625 [Vibrio parahaemolyticus]
GTGAGTAACAAAGAAAATAGTGTCGTCAGTTTTTACATTGACGACACCCCCACAGCTGAACAAGCTTCAAAAACCTTCCA
AGACGACTACGAACTGGACTTTCAAGATTTTATAGAAAGAACGGTAAATGAAAGTGCTGCTGAAGACTTCTCGTACTCAA
ATAATGGAGTAAAGAAAGCTGGAAGACGGCTTCGCAAGAGAGAGGGCGACCTCAAGTCAGCTACTGCTACAATCCAACAG
TTTCGAGCCGCACACGAAAAGCCATTAAACACTATCGCATATCTTGTTGGTCGCTGTTGCCGTGAACTGGGTATAGATGT
TAAACCAGTTACACGGTTAAAGCGCTTAGAAACAATCGTAGATAAGTTGCAGCGTAAATCTCTTGATGGTGAAACGGCAA
ATGCTACTTGTGTAACCAATATGAATGATATTGGCGGCTGCAGGGCGATTTTTCCGGATTTAATTTCATTGGAGAAGGTG
AAATCTCAACTGCAACTTACAGTTGAGAAGGTAGGCCGAGTTAGAATTAAAGATATTGATGACTATATTACTAGTCCTAA
ACCTAATGATTGTGGTTACCGAAGCTTGCATGTGATTTATCGCTATGACCATGCTAGTGGTAAAAGTTTTAACATTGAGG
CTCAGCTACGTACTCGACTTCAACATCTTTGGGCTACTACAGTGGAAATTGTCGACATCCTAGAAGGTACCAAGATTAAG
ACACACTCTCACAGTTCAAATGAAGGCAAGAGCAGTTTACAGGTTCAATGGGAAGAATTGCTTTCGATAATGAGCCAGTA
CATTGCTGATGCTGAAGGGGCTATAGAGCTAAGTGATATCGATAAAGCCAATTTTTCAAAGCGTCTGGTCGTCTTGGACC
GCGAAATCAATGCGCTGAATCGGTTGAGTAGTTTTAAAATTTTATCTGAAAAGGTTAATTCTTACTGTGATAGTTCCATT
GAGCACGTATTGCTAGTTATTAACGAAACTTCACGAGAATTGATCTTTAGTGAAGAGTTTGAAAATTACAGCCAAGCAAT
TTCAGTTTATAACGCAGCTGAGAAAGTCACTCGTAGCTACTCACGAGCAACCTCGAGACTCAATACCCTTCTCATATCCA
CAAAAAATATGGGCCAACTTTCGGAAGCCTACCCTAACTATCTAGGCGATTGTGCCTCATTCATCACTCTGCTTGAAGAC
GCAATGCTGTCTGGTGAAAGTTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17516.97 Da        Isoelectric Point: 7.9061

>AT115691 WP_005378671.1 NZ_CP034294:137938-138405 [Vibrio parahaemolyticus]
MKAYHTYSAVDVAWSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSSVI
TEQCDVALDQESESIVKDVVSKLGHLTGPQLVDLTHREGSPWHQVWDGTHQKVIPDHLIQAHYTQIKQSGRTASL

Download         Length: 468 bp

>AT115691 NZ_CP034294:137938-138405 [Vibrio parahaemolyticus]
ATGAAAGCATATCACACATACAGTGCTGTAGACGTTGCATGGAGCCTGCTCAAGCATGCGAAAGAGCAAGGTAAATGCTT
CTCCAATTTGCAGCTACAAAAACTTACCTATGTTTGTCATGGTTTATCATTGGCACACTTCCAGCGTCCTCTCGTCGTAG
ATGATGTATTTGCTTGGAAGTTTGGTCCAGTGGTGCCATCTGTTTACTTTCGCTTTAAATCTTATGGTAGTAGTGTGATC
ACTGAACAATGTGATGTAGCACTAGACCAAGAAAGTGAGTCTATTGTTAAAGATGTAGTCTCTAAGCTGGGCCATTTGAC
GGGGCCTCAACTTGTAGATTTAACTCACCGCGAAGGAAGTCCATGGCATCAGGTATGGGATGGCACACACCAAAAAGTGA
TTCCGGACCATTTGATTCAAGCCCATTACACTCAAATCAAACAATCTGGACGAACAGCTAGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References