Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966328..1966473 Replicon chromosome
Accession NZ_CP034281
Organism Klebsiella pneumoniae strain I72

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966364..1966466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966328..1966473 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI552_RS09860 1961458..1963518 + 2061 WP_004148850.1 oligopeptidase B -
EI552_RS09865 1963522..1964181 - 660 WP_032435029.1 exodeoxyribonuclease X -
EI552_RS09870 1964260..1964490 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EI552_RS09875 1964603..1964977 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EI552_RS09880 1964981..1965850 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
EI552_RS09885 1965867..1966205 + 339 WP_002911404.1 YebY family protein -
- 1966328..1966473 - 146 - - Antitoxin
- 1966364..1966466 + 103 - - Toxin
EI552_RS29175 1966841..1966984 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EI552_RS09895 1967089..1968057 - 969 WP_004151446.1 VirK/YbjX family protein -
EI552_RS09900 1968214..1968867 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
EI552_RS09905 1968864..1969055 - 192 WP_002911395.1 YebW family protein -
EI552_RS09910 1969153..1969392 - 240 WP_002911393.1 YebV family protein -
EI552_RS09915 1969508..1970941 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115663 NZ_CP034281:1966364-1966466 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115663 NZ_CP034281:c1966473-1966328 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References