Detailed information of TA system TA115657

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-HTH_XRE
• Location: 4770764..4771469
• Replicon: chromosome
• Accession: NZ_CP034276
• Organism: Pectobacterium versatile strain 14A

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EIP93_RS21620
• Protein ID: WP_125233255.1
• Coordinates: 4770764..4771189 (+)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EIP93_RS21625
• Protein ID: WP_103943792.1
• Coordinates: 4771170..4771469 (+)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIP93_RS21585	4765864..4766751	-	888	WP_010303217.1	sn-glycerol-3-phosphate ABC transporter permease UgpA	-
EIP93_RS21590	4766824..4768158	-	1335	WP_010303220.1	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	-
EIP93_RS21595	4768291..4768773	-	483	WP_125233253.1	GNAT family N-acetyltransferase	-
EIP93_RS21600	4768764..4769042	-	279	WP_125233370.1	DUF1778 domain-containing protein	-
EIP93_RS21605	4769153..4769569	-	417	WP_125233371.1	hypothetical protein	-
EIP93_RS21610	4769571..4770266	-	696	WP_125233254.1	hypothetical protein	-
EIP93_RS21620	4770764..4771189	+	426	WP_125233255.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EIP93_RS21625	4771170..4771469	+	300	WP_103943792.1	helix-turn-helix domain-containing protein	Antitoxin
EIP93_RS21630	4771493..4772254	-	762	WP_103862321.1	DeoR/GlpR family DNA-binding transcription regulator	-
EIP93_RS21635	4772593..4773507	+	915	WP_014917036.1	NAD(P)-dependent oxidoreductase	-
EIP93_RS21640	4773504..4774778	+	1275	WP_103862323.1	four-carbon acid sugar kinase family protein	-
EIP93_RS21645	4774775..4775431	+	657	WP_103862324.1	aldolase	-
EIP93_RS21650	4775465..4776247	+	783	WP_103862325.1	hydroxypyruvate isomerase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (3-123)

Antitoxin

• Cro/C1-type helix-turn-helix domain (46-86)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15549.98 Da
• Isoelectric Point: 8.1098

>T115657 WP_125233255.1 NZ_CP034276:4770764-4771189 [Pectobacterium versatile]
VAVYTTKLFDKKLKSEILSDCYLCEIAHEVMNGRFEGDLGGGVIKKRIALNAGKSAGARTIIFFKLGSNLFFADGWKKNQ
VRKGVKEIQDDELAVYKDIAGDLLQLTVQQIAQLVKVKELREVECDGCKDERAAGNGEKPA

Nucleotide

• Length: 426 bp

>T115657 NZ_CP034276:4770764-4771189 [Pectobacterium versatile]
GTGGCGGTATACACGACAAAGCTCTTCGATAAAAAACTAAAAAGCGAAATACTTTCAGATTGTTACCTTTGTGAGATTGC
TCATGAGGTAATGAATGGTCGCTTTGAGGGTGACCTTGGCGGTGGTGTGATTAAGAAACGAATCGCATTGAATGCCGGAA
AGAGTGCAGGAGCCAGAACTATCATCTTTTTCAAACTGGGCTCTAATCTATTTTTTGCCGATGGATGGAAAAAAAATCAG
GTCAGGAAAGGCGTTAAAGAAATTCAGGATGATGAGCTGGCTGTTTATAAAGACATTGCTGGTGACCTACTTCAACTCAC
CGTTCAACAAATAGCTCAATTGGTAAAAGTGAAAGAACTACGAGAGGTGGAATGCGATGGCTGCAAAGATGAAAGAGCTG
CAGGAAATGGCGAAAAGCCTGCATGA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 11209.74 Da
• Isoelectric Point: 10.0902

>AT115657 WP_103943792.1 NZ_CP034276:4771170-4771469 [Pectobacterium versatile]
MAKSLHEHGGITDTTMERINNRVAAREFRERIEQAHAMSGAEIQNMRSRYKMSQSSLAYALNMSVESVSKWERNEKKPSG
AALRLLNIINEKGLDIFAS

Nucleotide

• Length: 300 bp

>AT115657 NZ_CP034276:4771170-4771469 [Pectobacterium versatile]
ATGGCGAAAAGCCTGCATGAACACGGGGGTATCACTGATACCACAATGGAACGCATCAATAATCGGGTTGCAGCACGGGA
ATTCCGTGAACGCATCGAGCAAGCTCACGCAATGAGCGGTGCAGAAATTCAGAACATGCGCTCCCGTTATAAAATGTCGC
AATCTTCTTTAGCTTACGCTCTCAATATGTCCGTTGAGAGCGTCTCAAAATGGGAACGGAATGAGAAGAAACCCTCAGGG
GCTGCGCTACGTCTTCTCAATATAATCAACGAGAAAGGTCTGGATATTTTTGCCAGTTAG