Detailed information of TA system TA115656

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 4768291..4769042
• Replicon: chromosome
• Accession: NZ_CP034276
• Organism: Pectobacterium versatile strain 14A

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: EIP93_RS21595
• Protein ID: WP_125233253.1
• Coordinates: 4768291..4768773 (-)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: EIP93_RS21600
• Protein ID: WP_125233370.1
• Coordinates: 4768764..4769042 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIP93_RS21575	4763721..4764794	-	1074	WP_125233252.1	sn-glycerol-3-phosphate import ATP-binding protein UgpC	-
EIP93_RS21580	4764993..4765838	-	846	WP_039542012.1	sn-glycerol-3-phosphate ABC transporter permease UgpE	-
EIP93_RS21585	4765864..4766751	-	888	WP_010303217.1	sn-glycerol-3-phosphate ABC transporter permease UgpA	-
EIP93_RS21590	4766824..4768158	-	1335	WP_010303220.1	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	-
EIP93_RS21595	4768291..4768773	-	483	WP_125233253.1	GNAT family N-acetyltransferase	Toxin
EIP93_RS21600	4768764..4769042	-	279	WP_125233370.1	DUF1778 domain-containing protein	Antitoxin
EIP93_RS21605	4769153..4769569	-	417	WP_125233371.1	hypothetical protein	-
EIP93_RS21610	4769571..4770266	-	696	WP_125233254.1	hypothetical protein	-
EIP93_RS21620	4770764..4771189	+	426	WP_125233255.1	type II toxin-antitoxin system RelE/ParE family toxin	-
EIP93_RS21625	4771170..4771469	+	300	WP_103943792.1	helix-turn-helix domain-containing protein	-
EIP93_RS21630	4771493..4772254	-	762	WP_103862321.1	DeoR/GlpR family DNA-binding transcription regulator	-
EIP93_RS21635	4772593..4773507	+	915	WP_014917036.1	NAD(P)-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (39-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (10-87)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 17391.21 Da
• Isoelectric Point: 9.3654

>T115656 WP_125233253.1 NZ_CP034276:c4768773-4768291 [Pectobacterium versatile]
MGITAPGPLSAGHNLAEFCSQEPSLNEWLKKKALKNHSAGISRVYVICAEGTHQVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTENIALQVGVRALVVHALDENVRNFYLKFAFDPSPVQPLMLLYPIKI

Nucleotide

• Length: 483 bp

>T115656 NZ_CP034276:c4768773-4768291 [Pectobacterium versatile]
ATGGGAATAACTGCACCAGGGCCATTATCCGCCGGCCATAATCTTGCGGAATTTTGCAGCCAAGAACCGAGTTTGAATGA
ATGGCTAAAAAAGAAAGCGCTAAAAAATCATAGTGCAGGGATTTCCCGCGTATATGTTATTTGCGCTGAAGGCACCCATC
AGGTGATTGGATATTATTGTTTATCAACAGGTAGCGTTCAGAGAAATACGGCACCAGGTGCATATAGGCGCAATGCACCT
GAATCACTACCAGTCATTGTCCTTGGGCGGCTTGCCATTGATCAGGCGTATTCTGGTAAAGGTTTGGGTGTGGCTTTATT
AAAAGACGCGATATTTCGGACTGAGAATATTGCTTTGCAAGTGGGTGTGAGGGCATTAGTCGTTCACGCTCTGGATGAGA
ACGTGCGCAATTTCTACCTTAAATTCGCTTTTGATCCCTCGCCAGTGCAGCCCCTGATGCTACTCTACCCAATTAAAATT
TAG

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10623.11 Da
• Isoelectric Point: 4.4463

>AT115656 WP_125233370.1 NZ_CP034276:c4769042-4768764 [Pectobacterium versatile]
MKPETKEAPINIRAKASQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFILDNEQFDEFLAELDAPITAERQAR
INELMSRKSPWE

Nucleotide

• Length: 279 bp

>AT115656 NZ_CP034276:c4769042-4768764 [Pectobacterium versatile]
ATGAAACCTGAAACTAAAGAAGCGCCAATCAATATTCGGGCCAAAGCCTCCCAGCGGGACTTGATCGATATGGCTGCAAA
CCTTGTGTCAAAATCACGTACCGATTTTATGCTTGAAGCCGCCTGCCGCGAGGCGCAGGACATCTTGTTGGATCAACGTT
TGTTTATTCTGGACAACGAACAGTTTGACGAATTTTTGGCCGAGTTGGATGCACCTATCACCGCAGAGCGTCAGGCTCGC
ATTAACGAGCTGATGAGCCGCAAATCTCCATGGGAATAA