Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3518990..3519653 Replicon chromosome
Accession NZ_CP034276
Organism Pectobacterium versatile strain 14A

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag EIP93_RS15980 Protein ID WP_103940843.1
Coordinates 3518990..3519334 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag EIP93_RS15985 Protein ID WP_125232964.1
Coordinates 3519336..3519653 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIP93_RS15955 3514546..3515676 + 1131 WP_103971620.1 linear amide C-N hydrolase -
EIP93_RS15960 3515786..3516094 - 309 WP_103940851.1 hypothetical protein -
EIP93_RS15965 3516134..3516754 - 621 WP_103940849.1 FMN-dependent NADH-azoreductase -
EIP93_RS15970 3516789..3517562 - 774 WP_125232963.1 alpha/beta hydrolase -
EIP93_RS15975 3517730..3518758 + 1029 WP_107333256.1 helix-turn-helix domain-containing protein -
EIP93_RS15980 3518990..3519334 + 345 WP_103940843.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EIP93_RS15985 3519336..3519653 + 318 WP_125232964.1 helix-turn-helix domain-containing protein Antitoxin
EIP93_RS15990 3519868..3520083 - 216 WP_010279992.1 helix-turn-helix domain-containing protein -
EIP93_RS16000 3520669..3521247 - 579 WP_103183417.1 hypothetical protein -
EIP93_RS16005 3521717..3522043 + 327 WP_164498029.1 type II toxin-antitoxin system RelE/ParE family toxin -
EIP93_RS16010 3522048..3522386 + 339 WP_010279998.1 putative addiction module antidote protein -
EIP93_RS16015 3522478..3523080 - 603 WP_103941405.1 TetR/AcrR family transcriptional regulator -
EIP93_RS16020 3523198..3524121 + 924 WP_125233353.1 NADP-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12418.13 Da        Isoelectric Point: 9.7825

>T115652 WP_103940843.1 NZ_CP034276:3518990-3519334 [Pectobacterium versatile]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHLAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATQKPDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T115652 NZ_CP034276:3518990-3519334 [Pectobacterium versatile]
ATGAAATCACTCTACTGGGTTGGCAGTAGCAAAAAGGATCTCCAGTCGCTACCTGCAGATGTGCAGGATGTGTTCGGTTA
TGCACTTCATCTGGCTCAAACTGGTGGTAAACACACTCAAGCTAAGCCGCTGAAAGGTTTTGGTGGTGCGGGCGTATTAG
AAGTCGTTGAGGATTATATCGGCGATACTTATCGCGCAGTCTACACCGTCAAATTTGGAGAAGCAGTATACGTTCTACAT
GCTTTTCAGAAAAAATCGTCATCTGGAATTGCAACACAGAAACCCGATATGAACACCATTCGTGAACGCCTTAAAACCGC
AGAGAATCATGCAAAAGGAGCATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11390.44 Da        Isoelectric Point: 10.8066

>AT115652 WP_125232964.1 NZ_CP034276:3519336-3519653 [Pectobacterium versatile]
MSQDIEVSSGNVYADLGNLHAEGMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT115652 NZ_CP034276:3519336-3519653 [Pectobacterium versatile]
ATGAGCCAGGATATTGAAGTCAGCAGCGGTAATGTATACGCCGACCTTGGTAACTTGCATGCTGAAGGTATGTTGGTTAA
AGCGCAGCTTGCTACCCTGATTAGCTCAATCATCAAAAGCCGCCGTCTCACACAGGCAGAAGCAGCGAAGCTATTGGGCA
TGCCCCAACCAAAGCTATCCAACCTATTGCGTGGCCAATTCAGGGGAATCAGCGAAACCAAAATGCTGGAATGCCTTACA
AAGCTGGGGCGCGATATACAGATCGTTGTAGGGAAGCCACGCCGCACACCGGGTAGCGTTAAAGTCGTGTTTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References