Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1371509..1372134 Replicon chromosome
Accession NZ_CP034276
Organism Pectobacterium versatile strain 14A

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag EIP93_RS06175 Protein ID WP_005976087.1
Coordinates 1371509..1371712 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag EIP93_RS06180 Protein ID WP_005976089.1
Coordinates 1371766..1372134 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIP93_RS06145 1366973..1367311 + 339 WP_002208627.1 P-II family nitrogen regulator -
EIP93_RS06150 1367351..1368637 + 1287 WP_161973278.1 ammonium transporter AmtB -
EIP93_RS06155 1368772..1369635 - 864 WP_040031226.1 acyl-CoA thioesterase II -
EIP93_RS06160 1369848..1370429 + 582 WP_103941783.1 YbaY family lipoprotein -
EIP93_RS06165 1370449..1370769 - 321 WP_015839360.1 MGMT family protein -
EIP93_RS06175 1371509..1371712 - 204 WP_005976087.1 hemolysin expression modulator Hha Toxin
EIP93_RS06180 1371766..1372134 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
EIP93_RS06185 1372732..1372875 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
EIP93_RS06190 1372892..1373140 - 249 WP_015839361.1 type B 50S ribosomal protein L31 -
EIP93_RS06195 1373376..1376504 - 3129 WP_103941781.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T115647 WP_005976087.1 NZ_CP034276:c1371712-1371509 [Pectobacterium versatile]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T115647 NZ_CP034276:c1371712-1371509 [Pectobacterium versatile]
ATGAAAAAAATCGACTATTTGATGCGTTTGCGTAAATGCACAACCATTGACACTCTCGAACGCGTTATTGAAAAAAACAA
GTATGAACTCTCTAATGATGAACTGGAGATGTTCTTTTCCGCAGCCGATCATCGTCTGGCTGAACTGACAATGAACAAAC
TCTACGACAAAGTTCCTACCGCAGTATGGCGATACGTCCGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT115647 WP_005976089.1 NZ_CP034276:c1372134-1371766 [Pectobacterium versatile]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp

>AT115647 NZ_CP034276:c1372134-1371766 [Pectobacterium versatile]
ATGGATGAGTACACACCAAAACATTATGATATTGCCCAACTCAGATTCTTATGTGAGAATCTGTGTGACGAAAGCATAGC
AACGTTAGGTGATAGCAGTCACGGCTGGGTCAATGATCCAACATCTGCGATCAATCTCCAATTAAATGAACTTATTGAGC
ATATCGCTACGTTTATTCTCACATTTAAAATAAAATACCCTAACGAAAGTGAGCTTTCAGAGCAGGTTGAAAAGTATTTG
GATGATACTTACGTCTTGTTTAGCAACTATGGAATTAATGATGCTGAACTGCGGCGTTGGCAGAAGTCCAAAGCAAAATT
ATTCGGAATGTTCTCAGGGGAGAACGTCTGTACGCCTGCTAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References