Detailed information of TA system TA115646

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1115470..1116254
• Replicon: chromosome
• Accession: NZ_CP034276
• Organism: Pectobacterium versatile strain 14A

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: -
• Locus tag: EIP93_RS05090
• Protein ID: WP_116586074.1
• Coordinates: 1115760..1116254 (+)
• Length: 165 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: -
• Locus tag: EIP93_RS05085
• Protein ID: WP_125232377.1
• Coordinates: 1115470..1115763 (+)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIP93_RS05060	1110568..1111779	+	1212	WP_103861689.1	glycosyltransferase family 4 protein	-
EIP93_RS05065	1111781..1112893	+	1113	WP_039507741.1	glycosyltransferase family 4 protein	-
EIP93_RS05070	1112896..1113303	+	408	WP_039490298.1	hypothetical protein	-
EIP93_RS05075	1113342..1114736	+	1395	WP_125232376.1	DUF4832 domain-containing protein	-
EIP93_RS05080	1114763..1115263	+	501	WP_103861241.1	serine acetyltransferase	-
EIP93_RS05085	1115470..1115763	+	294	WP_125232377.1	DUF1778 domain-containing protein	Antitoxin
EIP93_RS05090	1115760..1116254	+	495	WP_116586074.1	GNAT family N-acetyltransferase	Toxin
EIP93_RS05095	1116316..1116486	+	171	Protein_983	helix-turn-helix domain-containing protein	-
EIP93_RS05100	1116933..1118075	+	1143	WP_125232378.1	Fic family protein	-
EIP93_RS05105	1118242..1120473	-	2232	WP_125232379.1	AAA family ATPase	-
EIP93_RS05110	1120959..1121225	-	267	WP_116227391.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (76-143)

Antitoxin

• Vibrio phage ICP1, Orf50 (14-88)

Sequences

Toxin

Protein

• Length: 165 a.a.
• Molecular weight: 17571.33 Da
• Isoelectric Point: 7.9094

>T115646 WP_116586074.1 NZ_CP034276:1115760-1116254 [Pectobacterium versatile]
MISAPEPLHAEHVFSSFGCGVESMDNWLKQRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEARNFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI

Nucleotide

• Length: 495 bp

>T115646 NZ_CP034276:1115760-1116254 [Pectobacterium versatile]
ATGATCTCAGCCCCTGAGCCACTTCACGCCGAACATGTATTTTCCTCATTCGGTTGCGGCGTGGAGTCTATGGACAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTCACTGGTGCATCGCGAACTTTTGTCAGTTGCGATGGCTCAAAAGTGCTGG
CCTATTACTCATTGGCCTCCAGTGCTGTAGCAACGAATGCCGCCCCCGGACGTTTTCGCCGCAATATGCCCGATCCGATT
CCGGTGGTAGTGCTGGGACGTCTGGCGGTGGATACGTCATTGCATGGTCAAGGTGTTGGCCGAGCGCTGGTGCGTGATGC
CGGGCTTCGGGTTATTCAGGTAGCGGACACTATCGGCATTCGCGGGATGTTGGTTCATGCGTTGTCTGATGAGGCGCGAA
ATTTTTACCTACGGGTGGGGTTTGAGCCTTCACCGATTGATCCCATGATGTTGATGGTAACGTTGGGGGATTTGGTGGGG
AGTTTATCAATTTGA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10958.58 Da
• Isoelectric Point: 10.1968

>AT115646 WP_125232377.1 NZ_CP034276:1115470-1115763 [Pectobacterium versatile]
MPVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEVLIDQRIIMADPDAYQEFLARLDQTPSPN
AALRKTMQTPAPWEQKK

Nucleotide

• Length: 294 bp

>AT115646 NZ_CP034276:1115470-1115763 [Pectobacterium versatile]
ATGCCAGTGACGAACAGCGTTTCTGTTAAACGCGAAACATTAAATTTACGCATCAAGCCCGCCGAACGAGATCTTATTGA
TCGTGCTGCGAAGGCCAGAGGAAAAAATCGCACTGATTTTGTCCTCGAAGCTGCTCGTGCCGCCGCAGAGGAAGTGTTGA
TCGATCAGCGCATCATCATGGCAGATCCCGATGCTTATCAGGAGTTCCTTGCTCGCTTGGATCAAACTCCCTCGCCGAAT
GCCGCGCTGCGCAAAACCATGCAAACACCTGCACCGTGGGAACAGAAAAAATGA