Detailed information of TA system TA115644

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 844614..845274
• Replicon: chromosome
• Accession: NZ_CP034276
• Organism: Pectobacterium versatile strain 14A

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: EIP93_RS03935
• Protein ID: WP_103861404.1
• Coordinates: 844861..845274 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A1V2R9A9
• Locus tag: EIP93_RS03930
• Protein ID: WP_039355397.1
• Coordinates: 844614..844880 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIP93_RS03910	840729..841733	-	1005	WP_103971793.1	substrate-binding domain-containing protein	-
EIP93_RS03915	841788..842396	-	609	WP_095701613.1	HD domain-containing protein	-
EIP93_RS03920	842675..843322	+	648	WP_103183036.1	hemolysin III family protein	-
EIP93_RS03925	843377..844378	-	1002	WP_116361860.1	tRNA-modifying protein YgfZ	-
EIP93_RS03930	844614..844880	+	267	WP_039355397.1	FAD assembly factor SdhE	Antitoxin
EIP93_RS03935	844861..845274	+	414	WP_103861404.1	protein YgfX	Toxin
EIP93_RS03940	845343..846278	+	936	WP_107332304.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
EIP93_RS03945	846344..846667	-	324	WP_010301820.1	hypothetical protein	-
EIP93_RS03950	846696..847214	-	519	WP_103971790.1	flavodoxin FldB	-
EIP93_RS03955	847554..847940	-	387	WP_103861400.1	thioesterase family protein	-
EIP93_RS03960	848165..849493	-	1329	WP_103861399.1	MHS family MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16359.31 Da
• Isoelectric Point: 10.7911

>T115644 WP_103861404.1 NZ_CP034276:844861-845274 [Pectobacterium versatile]
VAQWRCDLRVSWRMQLLSLVVHGLLVLFILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Nucleotide

• Length: 414 bp

>T115644 NZ_CP034276:844861-845274 [Pectobacterium versatile]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAGCTGCTGTCATTGGTGGTGCATGGCCTCTTAGTATT
ATTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAAATCGTTAAGCGGCCGTGGCTGCTGAAGAATGGCGTGTTGCTGTCATTACAAGCGGTTAACGCTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGCGATGATGAATGGCGTCACTTGCGTCAGCTTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10506.99 Da
• Isoelectric Point: 6.2223

>AT115644 WP_039355397.1 NZ_CP034276:844614-844880 [Pectobacterium versatile]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT115644 NZ_CP034276:844614-844880 [Pectobacterium versatile]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGTACGTTTGTACGTTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGAAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9A9