Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 401427..401958 Replicon chromosome
Accession NZ_CP034276
Organism Pectobacterium versatile strain 14A

Toxin (Protein)


Gene name stbE Uniprot ID A0A249QBN7
Locus tag EIP93_RS01840 Protein ID WP_039493031.1
Coordinates 401671..401958 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A3R8PFZ6
Locus tag EIP93_RS01835 Protein ID WP_039470361.1
Coordinates 401427..401681 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIP93_RS01810 396759..397349 - 591 WP_005975525.1 DnaA initiator-associating protein DiaA -
EIP93_RS01815 397538..397894 - 357 WP_039279491.1 YraN family protein -
EIP93_RS01820 397891..399909 - 2019 WP_125232179.1 penicillin-binding protein activator -
EIP93_RS01825 399971..400858 + 888 WP_116586249.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
EIP93_RS01835 401427..401681 + 255 WP_039470361.1 plasmid stabilization protein Antitoxin
EIP93_RS01840 401671..401958 + 288 WP_039493031.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EIP93_RS01845 402134..402919 + 786 WP_119158995.1 4,5-DOPA dioxygenase extradiol -
EIP93_RS01850 402988..404148 - 1161 WP_010297418.1 glutathionylspermidine synthase family protein -
EIP93_RS01855 404159..404833 - 675 WP_103861630.1 DUF1190 family protein -
EIP93_RS01860 405099..406493 - 1395 WP_103861629.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10993.93 Da        Isoelectric Point: 10.7694

>T115641 WP_039493031.1 NZ_CP034276:401671-401958 [Pectobacterium versatile]
MTYKLKFVPSALKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T115641 NZ_CP034276:401671-401958 [Pectobacterium versatile]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCATTGAAGGAATGGAAAAAATTAGGGCACCCTGTCCGGGAGCAGTTCAA
GAAAAAGCTGGTTGAGCGTTTGGAAAATCCTCGTGTTCCTTCAGCCCAACTTCATGGCCGTAAAGACCAGTATAAAATTA
AACTGAAGTCCGCTGGCTACAGGCTGGTGTATTTGGTCCAGGATGAGACCATTACTGTGATGGTTATGGGCGTTGGAAAG
CGCGAAGGTAGCCAGATTTATTCTGATACTAAAGGTCGCTCTGCTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9192.34 Da        Isoelectric Point: 3.7947

>AT115641 WP_039470361.1 NZ_CP034276:401427-401681 [Pectobacterium versatile]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
PDDL

Download         Length: 255 bp

>AT115641 NZ_CP034276:401427-401681 [Pectobacterium versatile]
ATGGCTTTCAACATCCTGACTAACACAGCCGCCAGTATTACTGAGTTGAAACGTGACCCGATGGGGACGGTACGGGCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGGAATGAGCCGGCGTTCTACTGTGTGCCTCCTGCCGTATTCGCTTATTTAA
TGGAACTGGCTGAAGATGCCGAACTGGGGCGTACCGTTGATGACCGGATGTCAGAACTAGCTGACGCGGAAGAGATTTCG
CCCGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A249QBN7

Antitoxin

Source ID Structure
AlphaFold DB A0A3R8PFZ6

References