Detailed information of TA system TA115640

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 166290..167730
• Replicon: chromosome
• Accession: NZ_CP034276
• Organism: Pectobacterium versatile strain 14A

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: EIP93_RS00740
• Protein ID: WP_103943073.1
• Coordinates: 166843..167730 (+)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: A0A7V8PRU9
• Locus tag: EIP93_RS00735
• Protein ID: WP_039474562.1
• Coordinates: 166290..166814 (+)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIP93_RS00705	161339..161665	-	327	WP_103943077.1	helix-turn-helix domain-containing protein	-
EIP93_RS00710	161763..162020	+	258	WP_039490198.1	helix-turn-helix domain-containing protein	-
EIP93_RS00715	162036..162353	-	318	WP_039533108.1	helix-turn-helix domain-containing protein	-
EIP93_RS00720	162630..163952	-	1323	WP_164498003.1	hypothetical protein	-
EIP93_RS00725	164124..164591	-	468	WP_125232137.1	DNA mismatch endonuclease Vsr	-
EIP93_RS00730	164599..166032	-	1434	WP_103183474.1	DNA cytosine methyltransferase	-
EIP93_RS00735	166290..166814	+	525	WP_039474562.1	hypothetical protein	Antitoxin
EIP93_RS00740	166843..167730	+	888	WP_103943073.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
EIP93_RS00745	167836..168699	-	864	WP_010300687.1	YicC family protein	-
EIP93_RS00750	168798..169706	-	909	WP_039542502.1	LysR family transcriptional regulator	-
EIP93_RS00755	170179..171126	-	948	WP_103943071.1	isoaspartyl peptidase/L-asparaginase	-
EIP93_RS00760	171186..172007	-	822	WP_103943069.1	M55 family metallopeptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 33993.89 Da
• Isoelectric Point: 5.7070

>T115640 WP_103943073.1 NZ_CP034276:166843-167730 [Pectobacterium versatile]
MLKQQIRQIVQSTPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKDANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYNIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHAIASELLNDGTPKNPFDMG

Nucleotide

• Length: 888 bp

>T115640 NZ_CP034276:166843-167730 [Pectobacterium versatile]
ATGCTGAAGCAACAAATTCGCCAAATCGTCCAGTCAACCCCTGACTATGCCGCAGTGACACCCGTCATAGAAAAAGAGAT
CTTGCATCATGACATTATCGATGTGCTGATCAAACAGGGCGTCATGCAGCGGTTAACGTTTATTGGCGGCACCTCATTAC
GAATGTGTTACAACAGTAGCAGGCTATCAGAAGATCTTGATTTCAATGGTGGTCATGATTTCCAGCCCTCAGCGTTTGAG
GGGCTGGAGTCCGAAATCCAAACCTATATTCAGAACAAGTATGAAACCGAAGTTTGGGTAAACAAACCTTCTGGCGAGCA
GCAAGGGGATACCGTTTCTTGGAAAATTAGTATCGTAAAAGACGCTAATCGTCCTGATTTGCCACGGCAAAAAATGCATA
TTGACGTCTGTGCTATTCCGTCATTTGATATTGAAAAACGCCCACTAATCAATCATTACAACATCGTTGTTCCGACTGAA
GGGATCTTGGTTCCGGTACAGTCGTTACAAGAAACATTGGCCGATAAGTTGATCGCGTTAGCGTATCGGGCAAGACGTAT
TAAACCTCGTGATATCTGGGATATTGTTTGGATTAAGCAGCGCGGTATTGATTTATCCAAGACACTGGTTGAAAAGAAGC
TCACCGCCAGACAGAAGCAAACAGAAGACTTTCGACAGGCGCTGTCTATTCAGTTAGCCAAGCTAATGTCGGAAGATGAA
GTCCGTGACGACTTCAATATGGAAATGAGCCGCTTTATTCCTAAGCAAATTAAAGAGAGAACCCTCGATAACCCTGAATA
TTGGGCTTATGTTCAGGGGGAGGTACATGCCATCGCGTCTGAGTTACTGAATGACGGAACACCAAAAAATCCATTTGATA
TGGGTTAG

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19332.49 Da
• Isoelectric Point: 9.0504

>AT115640 WP_039474562.1 NZ_CP034276:166290-166814 [Pectobacterium versatile]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT115640 NZ_CP034276:166290-166814 [Pectobacterium versatile]
ATGGCTAAATCTGATGAGCTATTAAACGCGTTGGCTAAAGCAGTGAACGCTGGCGGTGGCATTCACAGTGTAACAGAGCT
GGCTTTTATGCAGGGTGTGCCTTGTGACTCAGCCTTTAGAAAGTTCCTGGCAGATTGCGTAAAGAAGGGGTTGCTAAGAC
GAGTGGTGAAAGGCTTCTATGAAAGTGTTATTACACCACCTGAGCCTGAGACTGCCATTTATAAAATCATCAAAAAGTTG
CGCAGTGGCGTATTGAACTACATCAGCTTAGAAAGTCAGCTCAGTCATACCGGTGATATTTCACAAGTTGTGATGGGTAG
GGTCACGGTGGTGACTAAAGGTCGAAGTGGTTGTTTTGATACGCCTTATGGCGTGATCGAGCTTACCCATACTAAAAAGC
CAGTCGAGCAAATTGCACCTAATTTGTACTATGACCCTGACATCAAAATGTATCGCGCATACAAGGAACAAGCGATTGCA
GATCTAAAGCACTGCCAGCGCAATCTACATATGTTGGAGAGCTAA

Structures

Antitoxin

• AlphaFold DB: A0A7V8PRU9