115638

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 88172..88707 Replicon chromosome
Accession NZ_CP034276
Organism Pectobacterium versatile strain 14A

Toxin (Protein)


Gene name relE Uniprot ID C6DJA0
Locus tag EIP93_RS00365 Protein ID WP_015842269.1
Coordinates 88172..88459 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag EIP93_RS00370 Protein ID WP_010281712.1
Coordinates 88456..88707 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIP93_RS00345 83319..84161 + 843 WP_103160431.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
EIP93_RS00350 84290..85642 + 1353 WP_116361929.1 glutathione-disulfide reductase -
EIP93_RS00355 85839..87019 + 1181 Protein_65 DUF4935 domain-containing protein -
EIP93_RS00360 87021..87980 + 960 WP_103943153.1 bacteriophage abortive infection AbiH family protein -
EIP93_RS00365 88172..88459 - 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EIP93_RS00370 88456..88707 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EIP93_RS00375 88965..89870 + 906 WP_125232109.1 siderophore-interacting protein -
EIP93_RS00380 89905..90660 - 756 WP_125232110.1 thiol:disulfide interchange protein DsbG -
EIP93_RS00385 90939..91562 + 624 WP_125232111.1 LysE family translocator -
EIP93_RS00390 91623..92663 - 1041 WP_125232112.1 HipA domain-containing protein -
EIP93_RS00395 92660..92974 - 315 WP_116237915.1 HipA N-terminal domain-containing protein -
EIP93_RS00400 92959..93285 - 327 WP_125232113.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11074.15 Da        Isoelectric Point: 10.3527

>T115638 WP_015842269.1 NZ_CP034276:c88459-88172 [Pectobacterium versatile]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T115638 NZ_CP034276:c88459-88172 [Pectobacterium versatile]
ATGAGTTATAGCGTCAAATTCAGGGAAGATGCGCTAAAAGAATGGCTCAAGCTCGATAAAACCATTCAGCAGCAATTCGC
CAAAAAACTAAAGAAATGCTGCGAAAATCCCCATATTCCTTCGGCAAAGTTACGAGGGATGAAGGACTGCTACAAAATAA
AGCTCCGAGCGTCAGGCTTTCGTTTGGTTTATGAGGTTATTGACGACGTATTGATTATCGCAGTGGTAGCGGTAGGCAAA
CGTGAGCGCAGCGGTGTTTATCATCTGGCGAGTGAGCGGATGAGGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT115638 WP_010281712.1 NZ_CP034276:c88707-88456 [Pectobacterium versatile]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT115638 NZ_CP034276:c88707-88456 [Pectobacterium versatile]
ATGCCAAATATTATATTAAGCGATACCAGTGCCAGCGTCAGTGAACTGAAAAAGAACCCGATGGCGACGGTCAATGCTGG
TGATGGCCTGCCTGTCGCTATCTTGAACCGCAACCAACCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGACCAAGAATTGGTTAAGTTAATCGGTGAACGTAAAAACCAGCCGCTGGTCGACGTGGATTTGGAT
AGTTTCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S0XQ75

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References