Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1940416..1940561 Replicon chromosome
Accession NZ_CP034249
Organism Klebsiella pneumoniae strain KP18-29

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1940452..1940554 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1940416..1940561 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIL78_RS09695 1935549..1937609 + 2061 WP_019705169.1 oligopeptidase B -
EIL78_RS09700 1937613..1938270 - 658 Protein_1863 exodeoxyribonuclease X -
EIL78_RS09705 1938349..1938579 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EIL78_RS09710 1938692..1939066 + 375 WP_014343244.1 CopC domain-containing protein YobA -
EIL78_RS09715 1939070..1939939 + 870 WP_014343243.1 copper homeostasis membrane protein CopD -
EIL78_RS09720 1939956..1940294 + 339 WP_002911404.1 YebY family protein -
- 1940416..1940561 - 146 - - Antitoxin
- 1940452..1940554 + 103 - - Toxin
EIL78_RS27245 1940929..1941072 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EIL78_RS09730 1941177..1942145 - 969 WP_004151446.1 VirK/YbjX family protein -
EIL78_RS09735 1942302..1942955 + 654 WP_014343242.1 protein-serine/threonine phosphatase -
EIL78_RS09740 1942952..1943143 - 192 WP_002911395.1 YebW family protein -
EIL78_RS09745 1943241..1943480 - 240 WP_002911393.1 YebV family protein -
EIL78_RS09750 1943596..1945029 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115605 NZ_CP034249:1940452-1940554 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115605 NZ_CP034249:c1940561-1940416 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References