Detailed information of TA system TA115598

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 3449180..3449822
• Replicon: chromosome
• Accession: NZ_CP034246
• Organism: Shewanella algae strain VGH117

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: EIY89_RS15355
• Protein ID: WP_025887841.1
• Coordinates: 3449180..3449602 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: EIY89_RS15360
• Protein ID: WP_190535955.1
• Coordinates: 3449583..3449822 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIY89_RS15330	3444697..3445176	-	480	WP_190532851.1	SoxR reducing system RseC family protein	-
EIY89_RS15335	3445187..3446119	-	933	WP_190532853.1	MucB/RseB C-terminal domain-containing protein	-
EIY89_RS15340	3446129..3446749	-	621	WP_190532857.1	anti-sigma factor	-
EIY89_RS15345	3446774..3447352	-	579	WP_025010551.1	RNA polymerase sigma factor RpoE	-
EIY89_RS15350	3447552..3449162	+	1611	WP_190532860.1	L-aspartate oxidase	-
EIY89_RS15355	3449180..3449602	-	423	WP_025887841.1	hypothetical protein	Toxin
EIY89_RS15360	3449583..3449822	-	240	WP_190535955.1	succinate dehydrogenase assembly factor 2	Antitoxin
EIY89_RS15365	3449921..3450829	-	909	WP_025010548.1	transcriptional activator NhaR	-
EIY89_RS15370	3450846..3451214	-	369	WP_096141176.1	hypothetical protein	-
EIY89_RS15375	3451226..3452401	-	1176	WP_025010547.1	Na+/H+ antiporter NhaA	-
EIY89_RS15380	3452519..3453313	-	795	WP_025887839.1	thymidylate synthase	-
EIY89_RS15385	3453313..3454140	-	828	WP_025010545.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-135)

Antitoxin

• Flavinator of succinate dehydrogenase (5-75)

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 16336.82 Da
• Isoelectric Point: 7.6048

>T115598 WP_025887841.1 NZ_CP034246:c3449602-3449180 [Shewanella algae]
VAGQRHRFQLSSSFSQYLSLTVLAAICLSSFLAWPALDYPFYLSFKYLCLLLMLAGFGLALWRLRRWQLCFWLNELGEGQ
FEPGSSFELSGRPWVSPFVVTFTYQGEDNYGRCWLFADMFDDTDYRHLCRLLLQRSKSAN

Nucleotide

• Length: 423 bp

>T115598 NZ_CP034246:c3449602-3449180 [Shewanella algae]
GTGGCCGGGCAGCGCCATAGGTTTCAACTCAGTTCTTCCTTCAGCCAGTATCTGAGTCTGACGGTGCTGGCTGCTATTTG
CCTGAGCAGCTTTCTTGCCTGGCCGGCGCTGGATTATCCTTTCTATTTATCGTTCAAATACCTATGTTTACTGCTAATGC
TGGCGGGCTTTGGCCTTGCACTGTGGCGTTTGCGCCGTTGGCAACTCTGTTTCTGGCTTAATGAATTGGGTGAAGGACAG
TTCGAACCCGGTTCGAGTTTCGAACTTAGTGGCAGACCTTGGGTCAGCCCCTTTGTGGTGACTTTTACCTATCAGGGGGA
GGATAACTACGGGCGTTGCTGGCTGTTTGCCGATATGTTTGACGACACAGACTATCGTCACCTGTGTCGTCTATTGTTGC
AGCGCTCAAAGTCCGCTAACTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9246.75 Da
• Isoelectric Point: 5.6627

>AT115598 WP_190535955.1 NZ_CP034246:c3449822-3449583 [Shewanella algae]
MSTPRVKWACRRGMLELDVLFQPFVEQHYETLSPENKALFVRLLECEDPELFAWFMGHEQCPDPQLAQMVVRVRGRAAP

Nucleotide

• Length: 240 bp

>AT115598 NZ_CP034246:c3449822-3449583 [Shewanella algae]
ATGAGTACCCCCAGAGTTAAGTGGGCATGTCGCCGTGGTATGCTGGAGCTTGATGTACTGTTTCAACCCTTTGTGGAACA
GCATTACGAGACTCTGAGCCCTGAGAATAAGGCCTTGTTTGTTCGTCTGCTTGAGTGTGAAGATCCTGAGCTCTTTGCCT
GGTTTATGGGGCATGAGCAATGTCCGGATCCGCAACTGGCACAGATGGTAGTGCGCGTTCGTGGCCGGGCAGCGCCATAG