115596

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 780706..782255 Replicon chromosome
Accession NZ_CP034246
Organism Shewanella algae strain VGH117

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag EIY89_RS03615 Protein ID WP_190534547.1
Coordinates 780706..782007 (-) Length 434 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag EIY89_RS03620 Protein ID WP_025011264.1
Coordinates 782007..782255 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIY89_RS03600 776205..776789 + 585 WP_117200305.1 LysE family translocator -
EIY89_RS03605 776867..778894 - 2028 WP_071237209.1 S9 family peptidase -
EIY89_RS03610 779198..780565 + 1368 WP_028781110.1 L-cystine transporter -
EIY89_RS03615 780706..782007 - 1302 WP_190534547.1 type II toxin-antitoxin system HipA family toxin Toxin
EIY89_RS03620 782007..782255 - 249 WP_025011264.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
EIY89_RS03625 782769..784460 + 1692 WP_190534550.1 ATP-binding cassette domain-containing protein -
EIY89_RS03630 784473..784847 - 375 WP_190534553.1 PH domain-containing protein -
EIY89_RS03635 784858..786783 - 1926 WP_190534555.1 U32 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-402)

Antitoxin

Cro/C1-type helix-turn-helix domain

(15-64)


Sequences

Toxin        


Download         Length: 434 a.a.        Molecular weight: 48767.58 Da        Isoelectric Point: 9.4581

>T115596 WP_190534547.1 NZ_CP034246:c782007-780706 [Shewanella algae]
MQKLIAYMNGELVGTLAKHKNGAHTFQYDKDWITNAMARPLSLSLRLQLPTITSDAVINYFDNLLPDSPQVRDRIVARYK
ASSKQPFDLLKEIGKDSVGAIALFPPEHPYKKEPLSYEVLDEKKLEAVLSAYKSDIPLGMLKEEEDFRISVAGAQEKTAL
LFIDGQWCIPKGNTPTTHIIKLPIGEIQQANATLDLKDSVENEFLCIELARALEFAVPSVNIIKTDNLKALAVERFDRRW
TKDRAGLLRLPQEDICQVFGMPSSIKYESQGGPGIEQIMKLLMGSSNALEDRYSFMRFQVFQWIIGATDGHAKNFSIYID
RGGSYRLTPFYDILSAYPLLGGKGLNIRQLKLAMGLKATKGKKYEINKILPRHFLDTAKAVNFSQDKMQRIMDEMKGALP
KAISQVRANLPEGFPEHISNSIFENAKKIIKKI

Download         Length: 1302 bp

>T115596 NZ_CP034246:c782007-780706 [Shewanella algae]
ATGCAAAAGCTAATAGCATACATGAATGGTGAACTTGTTGGCACCTTGGCGAAGCATAAGAACGGCGCTCACACTTTTCA
ATATGATAAGGACTGGATAACCAATGCAATGGCTCGCCCACTGTCATTGTCTTTGAGGCTTCAATTACCGACTATCACTT
CCGATGCCGTTATCAACTATTTTGACAACCTCTTACCAGACAGCCCACAAGTCAGAGATAGGATCGTTGCAAGGTACAAA
GCCTCGTCCAAACAACCATTTGATCTCTTGAAAGAAATTGGAAAGGATAGTGTTGGTGCTATTGCACTATTTCCTCCCGA
ACACCCCTATAAAAAAGAGCCACTCAGCTACGAAGTATTGGATGAGAAGAAACTAGAGGCGGTTCTTTCTGCATACAAGT
CTGATATCCCCCTCGGGATGCTCAAAGAGGAAGAAGACTTTAGAATCTCAGTGGCAGGTGCTCAAGAAAAAACCGCACTC
TTATTCATTGATGGACAATGGTGTATACCGAAAGGAAACACCCCAACCACTCACATTATCAAGCTGCCAATAGGCGAAAT
ACAACAAGCTAACGCGACACTGGATCTCAAAGATAGCGTAGAAAATGAGTTTCTTTGCATTGAGCTAGCGAGAGCTCTGG
AATTCGCAGTTCCCAGCGTCAATATAATCAAAACAGACAACCTTAAAGCTTTAGCTGTAGAACGATTTGATCGACGCTGG
ACAAAAGACAGAGCAGGCTTGCTACGCTTACCTCAAGAAGATATTTGCCAAGTGTTTGGTATGCCATCATCCATCAAATA
TGAATCTCAAGGTGGTCCAGGCATAGAACAGATCATGAAGTTATTAATGGGCTCAAGTAATGCACTTGAAGATCGATATA
GCTTCATGAGATTCCAGGTATTTCAATGGATCATTGGGGCTACGGATGGACATGCTAAAAACTTTTCTATCTATATTGAT
AGAGGAGGTAGCTATCGACTCACTCCATTCTACGACATTCTGTCGGCCTACCCATTACTGGGAGGAAAAGGACTCAATAT
TAGACAACTTAAGCTCGCAATGGGATTAAAAGCCACAAAAGGCAAGAAGTACGAAATCAATAAAATCCTGCCTCGTCACT
TTTTAGATACTGCTAAAGCTGTGAATTTTAGTCAGGATAAGATGCAAAGAATAATGGATGAAATGAAAGGTGCGTTACCT
AAGGCAATCTCGCAAGTAAGGGCGAATCTACCAGAGGGCTTTCCAGAGCATATCTCCAACTCAATTTTTGAGAATGCCAA
GAAAATAATTAAAAAAATCTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9366.70 Da        Isoelectric Point: 6.2564

>AT115596 WP_025011264.1 NZ_CP034246:c782255-782007 [Shewanella algae]
MIYSPKQLADMMLLIRQKNGWTQSELAKKVGIKQATISNFENNPNKTTLSTFFKLVQAMDLTLSIQEKTQLTSPSENDDE
SW

Download         Length: 249 bp

>AT115596 NZ_CP034246:c782255-782007 [Shewanella algae]
ATGATATATAGTCCAAAGCAACTCGCAGATATGATGCTACTGATACGCCAAAAGAATGGCTGGACTCAGTCAGAGTTGGC
GAAAAAAGTCGGTATAAAGCAAGCAACAATCTCGAACTTCGAGAACAACCCCAACAAAACAACGCTTTCTACCTTCTTTA
AGCTTGTACAAGCTATGGATCTAACACTGAGTATCCAAGAAAAAACACAGCTGACTTCGCCAAGTGAAAATGATGATGAG
AGTTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References