Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 531693..532276 Replicon chromosome
Accession NZ_CP034237
Organism Pectobacterium carotovorum subsp. carotovorum strain JR1.1

Toxin (Protein)


Gene name parE Uniprot ID A0A7V8PTK4
Locus tag EH204_RS02350 Protein ID WP_010296214.1
Coordinates 531971..532276 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8PT23
Locus tag EH204_RS02345 Protein ID WP_010296210.1
Coordinates 531693..531983 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EH204_RS02325 526827..528089 - 1263 WP_161508747.1 L-rhamnose isomerase -
EH204_RS02330 528086..529576 - 1491 WP_161508748.1 rhamnulokinase -
EH204_RS02335 529913..530752 + 840 WP_039493893.1 HTH-type transcriptional activator RhaS -
EH204_RS02340 530777..531631 + 855 WP_161508749.1 helix-turn-helix domain-containing protein -
EH204_RS02345 531693..531983 + 291 WP_010296210.1 ribbon-helix-helix protein, CopG family Antitoxin
EH204_RS02350 531971..532276 + 306 WP_010296214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EH204_RS02355 532396..534102 - 1707 WP_161508750.1 ABC transporter ATP-binding protein -
EH204_RS02360 534099..534965 - 867 WP_040031931.1 ABC transporter permease -
EH204_RS02365 534958..535917 - 960 WP_029367586.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11576.44 Da        Isoelectric Point: 9.8325

>T115570 WP_010296214.1 NZ_CP034237:531971-532276 [Pectobacterium carotovorum subsp. carotovorum]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTGRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T115570 NZ_CP034237:531971-532276 [Pectobacterium carotovorum subsp. carotovorum]
ATGCCACAAGTGATCGTTTCAGAACGCGCGAGGCGTGATTTGCAGCGCCTACAGGATTTTCTAAAAAACAAAAATGCGCT
GGCCGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCAGTGG
AACATCTTCCCCTTGAATATCAAGAGTTGGTGATCGAATTCGGCAGCAGCGGGTATGTGATGCTTTACCGTCACGATGAG
CTGACCGGCAGAGTGGTGATACTGACCGTTAAACATCAAAAAGAAGCTGGTTATCAAAACCCGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11064.13 Da        Isoelectric Point: 4.7692

>AT115570 WP_010296210.1 NZ_CP034237:531693-531983 [Pectobacterium carotovorum subsp. carotovorum]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT115570 NZ_CP034237:531693-531983 [Pectobacterium carotovorum subsp. carotovorum]
ATGGCTGACACCACACGTCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGCTGGCTGATGA
CCGCAACAGCTCAGCCCATGCGCTGATGCTGGAAGCAATTGCCGAATACGTTGAACGGGAAGAAAAACGCAGCCAGTATC
GTAAAGAGGCGTTGGCCGCGTGGGAAGACTATCAGGACACTGGCAAACATATCACCGCAGATGAGACCGTTACCTGGTTA
GAATCCTGGGGTTCTGGACATGAACAGGATGCGCCTGCATGCCACAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8PTK4

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8PT23

References