Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 4276279..4276862 | Replicon | chromosome |
Accession | NZ_CP034236 | ||
Organism | Pectobacterium carotovorum subsp. carotovorum strain BP201601.1 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A7V8PTK4 |
Locus tag | EH203_RS19135 | Protein ID | WP_010296214.1 |
Coordinates | 4276279..4276584 (-) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7V8PT23 |
Locus tag | EH203_RS19140 | Protein ID | WP_010296210.1 |
Coordinates | 4276572..4276862 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EH203_RS19120 | 4272638..4273597 | + | 960 | WP_029367586.1 | ABC transporter permease | - |
EH203_RS19125 | 4273590..4274456 | + | 867 | WP_010296221.1 | ABC transporter permease | - |
EH203_RS19130 | 4274453..4276159 | + | 1707 | WP_161502916.1 | ABC transporter ATP-binding protein | - |
EH203_RS19135 | 4276279..4276584 | - | 306 | WP_010296214.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
EH203_RS19140 | 4276572..4276862 | - | 291 | WP_010296210.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
EH203_RS19145 | 4276924..4277778 | - | 855 | WP_029367584.1 | helix-turn-helix domain-containing protein | - |
EH203_RS19150 | 4277803..4278642 | - | 840 | WP_010296204.1 | HTH-type transcriptional activator RhaS | - |
EH203_RS19155 | 4278979..4280469 | + | 1491 | WP_010296202.1 | rhamnulokinase | - |
EH203_RS19160 | 4280466..4281728 | + | 1263 | WP_010296200.1 | L-rhamnose isomerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11576.44 Da Isoelectric Point: 9.8325
>T115564 WP_010296214.1 NZ_CP034236:c4276584-4276279 [Pectobacterium carotovorum subsp. carotovorum]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTGRVVILTVKHQKEAGYQNP
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTGRVVILTVKHQKEAGYQNP
Download Length: 306 bp
>T115564 NZ_CP034236:c4276584-4276279 [Pectobacterium carotovorum subsp. carotovorum]
ATGCCACAAGTGATCGTTTCAGAACGCGCGAGGCGTGATTTGCAGCGTCTACAGGATTTTCTAAAAAACAAAAATGCGCT
GGCCGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCAGTGG
AACATCTTCCCCTTGAATATCAAGAGTTGGTGATCGAATTCGGCAGCAGCGGGTATGTGATGCTTTACCGTCACGATGAG
CTGACCGGCAGAGTGGTGATACTGACCGTTAAACATCAAAAAGAAGCTGGTTATCAAAACCCGTAA
ATGCCACAAGTGATCGTTTCAGAACGCGCGAGGCGTGATTTGCAGCGTCTACAGGATTTTCTAAAAAACAAAAATGCGCT
GGCCGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCAGTGG
AACATCTTCCCCTTGAATATCAAGAGTTGGTGATCGAATTCGGCAGCAGCGGGTATGTGATGCTTTACCGTCACGATGAG
CTGACCGGCAGAGTGGTGATACTGACCGTTAAACATCAAAAAGAAGCTGGTTATCAAAACCCGTAA
Antitoxin
Download Length: 97 a.a. Molecular weight: 11064.13 Da Isoelectric Point: 4.7692
>AT115564 WP_010296210.1 NZ_CP034236:c4276862-4276572 [Pectobacterium carotovorum subsp. carotovorum]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK
Download Length: 291 bp
>AT115564 NZ_CP034236:c4276862-4276572 [Pectobacterium carotovorum subsp. carotovorum]
ATGGCTGACACCACACGTCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGCTGGCCGATGA
CCGCAACAGCTCAGCCCATGCGCTGATGCTGGAAGCGATTGCCGAATACGTTGAACGGGAAGAAAAACGCAGCCAGTACC
GTAAAGAGGCGTTGGCCGCGTGGGAAGACTATCAGGACACTGGCAAACATATCACCGCAGATGAGACCGTTACCTGGTTA
GAATCCTGGGGTTCTGGACATGAACAGGATGCGCCTGCATGCCACAAGTGA
ATGGCTGACACCACACGTCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGCTGGCCGATGA
CCGCAACAGCTCAGCCCATGCGCTGATGCTGGAAGCGATTGCCGAATACGTTGAACGGGAAGAAAAACGCAGCCAGTACC
GTAAAGAGGCGTTGGCCGCGTGGGAAGACTATCAGGACACTGGCAAACATATCACCGCAGATGAGACCGTTACCTGGTTA
GAATCCTGGGGTTCTGGACATGAACAGGATGCGCCTGCATGCCACAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8PTK4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8PT23 |