Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4030413..4031073 Replicon chromosome
Accession NZ_CP034236
Organism Pectobacterium carotovorum subsp. carotovorum strain BP201601.1

Toxin (Protein)


Gene name cptA Uniprot ID A0A419ATT9
Locus tag EH203_RS18040 Protein ID WP_029368427.1
Coordinates 4030413..4030826 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag EH203_RS18045 Protein ID WP_005971623.1
Coordinates 4030807..4031073 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EH203_RS18015 4026211..4027539 + 1329 WP_010301826.1 MHS family MFS transporter -
EH203_RS18020 4027747..4028133 + 387 WP_010301824.1 thioesterase family protein -
EH203_RS18025 4028473..4028991 + 519 WP_010301821.1 flavodoxin FldB -
EH203_RS18030 4029020..4029343 + 324 WP_010301820.1 hypothetical protein -
EH203_RS18035 4029409..4030344 - 936 WP_010301818.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
EH203_RS18040 4030413..4030826 - 414 WP_029368427.1 protein YgfX Toxin
EH203_RS18045 4030807..4031073 - 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
EH203_RS18050 4031309..4032310 + 1002 WP_010301809.1 tRNA-modifying protein YgfZ -
EH203_RS18055 4032365..4033012 - 648 WP_010301806.1 hemolysin III family protein -
EH203_RS18060 4033291..4033899 + 609 WP_010301802.1 HD domain-containing protein -
EH203_RS18065 4033954..4034958 + 1005 WP_010301796.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16296.29 Da        Isoelectric Point: 10.7911

>T115562 WP_029368427.1 NZ_CP034236:c4030826-4030413 [Pectobacterium carotovorum subsp. carotovorum]
VALWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T115562 NZ_CP034236:c4030826-4030413 [Pectobacterium carotovorum subsp. carotovorum]
GTGGCCCTGTGGCGATGTGACCTTCGTGTTTCATGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTACGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAACGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTATTACTGTCATTACAAGCGGTTAACGGTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGCGATGATGAATGGCGTCACTTGCGTCAAATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT115562 WP_005971623.1 NZ_CP034236:c4031073-4030807 [Pectobacterium carotovorum subsp. carotovorum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT115562 NZ_CP034236:c4031073-4030807 [Pectobacterium carotovorum subsp. carotovorum]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGCACGTTTGTACGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCTGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A419ATT9

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References