Detailed information of TA system TA115561

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3928194..3928719
• Replicon: chromosome
• Accession: NZ_CP034236
• Organism: Pectobacterium carotovorum subsp. carotovorum strain BP201601.1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EH203_RS17635
• Protein ID: WP_161502853.1
• Coordinates: 3928435..3928719 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: C6D956
• Locus tag: EH203_RS17630
• Protein ID: WP_005973616.1
• Coordinates: 3928194..3928445 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EH203_RS17600	3924360..3924620	+	261	WP_039488126.1	AlpA family transcriptional regulator	-
EH203_RS17605	3924617..3924841	+	225	WP_161502850.1	hypothetical protein	-
EH203_RS17610	3924850..3925209	+	360	Protein_3450	ash family protein	-
EH203_RS17615	3925197..3925394	+	198	WP_161502851.1	host cell division inhibitor Icd-like protein	-
EH203_RS17620	3925387..3925599	+	213	WP_161503083.1	hypothetical protein	-
EH203_RS17625	3925610..3927934	+	2325	WP_161502852.1	toprim domain-containing protein	-
EH203_RS17630	3928194..3928445	+	252	WP_005973616.1	prevent-host-death protein	Antitoxin
EH203_RS17635	3928435..3928719	+	285	WP_161502853.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EH203_RS17640	3928936..3929817	-	882	WP_202618479.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
EH203_RS17645	3929801..3930346	-	546	WP_107332344.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	-
EH203_RS17650	3930604..3931137	+	534	WP_161503084.1	hypothetical protein	-
EH203_RS17655	3931507..3932288	+	782	Protein_3459	transporter substrate-binding domain-containing protein	-
EH203_RS17660	3932544..3933170	+	627	WP_039539927.1	LysE family transporter	-
EH203_RS17665	3933215..3933697	-	483	WP_039507819.1	GNAT family N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11081.05 Da
• Isoelectric Point: 10.1005

>T115561 WP_161502853.1 NZ_CP034236:3928435-3928719 [Pectobacterium carotovorum subsp. carotovorum]
MSYKLEFEEHALKEFKKLGSPVREQFTKKLKELLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEYEIVVLILAVGK
RERSEVYKTAKDRL

Nucleotide

• Length: 285 bp

>T115561 NZ_CP034236:3928435-3928719 [Pectobacterium carotovorum subsp. carotovorum]
ATGAGTTATAAGCTGGAGTTTGAAGAGCACGCACTGAAAGAATTTAAGAAGCTGGGTTCACCCGTTCGGGAGCAGTTCAC
CAAAAAACTGAAAGAGCTTTTACAAAATCCCCACGTTCCCGCCAACCGGCTTCACGGAATGGCTGACTGCTACAAAATCA
AACTTCGTTCCGCTGGTTATCGGCTAGTGTATCAAGTGCTTGAGTATGAGATCGTGGTGCTGATTTTAGCGGTGGGCAAA
CGGGAACGGTCAGAAGTTTATAAAACAGCGAAAGACCGACTATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9079.35 Da
• Isoelectric Point: 5.0807

>AT115561 WP_005973616.1 NZ_CP034236:3928194-3928445 [Pectobacterium carotovorum subsp. carotovorum]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Nucleotide

• Length: 252 bp

>AT115561 NZ_CP034236:3928194-3928445 [Pectobacterium carotovorum subsp. carotovorum]
ATGTCCGTACAACCTATCCTTGCAAATGCAGCCGTGAGTATCAGCGACTTTAAAAAGTCCCCTAATGCCGCGCTTAAAGA
AGCTAACGGCGAGCCTGTAGCCGTGCTAACCAATGGCCGTATCTCTGGCTATTATGTTTCTCCTGAAACATGGGAAGCAC
TGGCCGATTATCAGGAAGATATCGAACTCGCCAAAATTGCCCGTTCCCGGATGAAGGGGAAACGTGTGAAGGTCGATCTG
GATGAGTTATAA

Structures

Antitoxin

• AlphaFold DB: A0A0G4JQP6