Detailed information of TA system TA115557

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 2877589..2878159
• Replicon: chromosome
• Accession: NZ_CP034236
• Organism: Pectobacterium carotovorum subsp. carotovorum strain BP201601.1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EH203_RS12925
• Protein ID: WP_161502587.1
• Coordinates: 2877589..2877873 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EH203_RS12930
• Protein ID: WP_161503064.1
• Coordinates: 2877920..2878159 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EH203_RS12915	2875401..2877083	+	1683	WP_161502586.1	DUF262 domain-containing HNH endonuclease family protein	-
EH203_RS12920	2877354..2877599	+	246	WP_010286544.1	CopG family ribbon-helix-helix protein	-
EH203_RS12925	2877589..2877873	+	285	WP_161502587.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EH203_RS12930	2877920..2878159	+	240	WP_161503064.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
EH203_RS12935	2878217..2878576	+	360	WP_161502588.1	hypothetical protein	-
EH203_RS12940	2878927..2879610	+	684	Protein_2536	integrase arm-type DNA-binding domain-containing protein	-
EH203_RS12945	2879645..2879879	+	235	Protein_2537	hypothetical protein	-
EH203_RS12950	2879855..2880151	+	297	WP_049776225.1	type II toxin-antitoxin system RelE/ParE family toxin	-
EH203_RS12955	2880563..2881441	+	879	WP_010294834.1	hypothetical protein	-
EH203_RS12960	2881609..2882073	-	465	WP_029367307.1	GyrI-like domain-containing protein	-
EH203_RS12965	2882222..2882944	-	723	WP_010294838.1	alpha/beta fold hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (2-77)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11099.93 Da
• Isoelectric Point: 10.2808

>T115557 WP_161502587.1 NZ_CP034236:2877589-2877873 [Pectobacterium carotovorum subsp. carotovorum]
MEIKWLRKAAANLEAEYRYIAQGDPQAASQFVDEVQRLTELLPQQPAMGRPGRVLGTRELVLTHYPYIIPYRVKDNMIQI
LRVFHTHRRLPTKW

Nucleotide

• Length: 285 bp

>T115557 NZ_CP034236:2877589-2877873 [Pectobacterium carotovorum subsp. carotovorum]
ATGGAAATTAAATGGCTGCGTAAAGCTGCGGCCAATTTGGAAGCCGAGTACCGCTATATCGCGCAAGGCGATCCACAAGC
CGCCAGCCAGTTCGTAGATGAAGTCCAACGGTTAACGGAATTACTACCGCAACAGCCAGCAATGGGAAGACCTGGCCGTG
TACTTGGAACGCGTGAACTTGTGTTAACGCACTATCCCTACATCATCCCCTACCGCGTGAAAGATAATATGATCCAGATT
CTGCGCGTTTTTCATACGCACAGGCGTTTACCCACAAAATGGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9228.68 Da
• Isoelectric Point: 6.3649

>AT115557 WP_161503064.1 NZ_CP034236:2877920-2878159 [Pectobacterium carotovorum subsp. carotovorum]
MGNVTFRIDDDLKRRSYAALKKLGITPSEALRLTLEYVAESERLPFKQKLLNDEDVELVEVVRERLRNPKPVRMTLDDL

Nucleotide

• Length: 240 bp

>AT115557 NZ_CP034236:2877920-2878159 [Pectobacterium carotovorum subsp. carotovorum]
ATGGGTAATGTTACTTTCCGTATCGATGACGATCTGAAAAGGCGCTCTTATGCAGCACTGAAGAAACTGGGTATTACGCC
TTCTGAGGCATTGCGCCTTACGTTGGAATACGTTGCTGAAAGTGAAAGACTCCCATTTAAACAAAAGTTACTCAATGATG
AAGACGTAGAATTAGTTGAAGTTGTCCGTGAACGCCTTCGCAACCCCAAACCAGTACGCATGACGCTGGATGATCTTTAG