Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1072108..1072633 Replicon chromosome
Accession NZ_CP034236
Organism Pectobacterium carotovorum subsp. carotovorum strain BP201601.1

Toxin (Protein)


Gene name relE Uniprot ID A0A1D7Z1B4
Locus tag EH203_RS04740 Protein ID WP_005973612.1
Coordinates 1072349..1072633 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6D956
Locus tag EH203_RS04735 Protein ID WP_005973616.1
Coordinates 1072108..1072359 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EH203_RS04715 1069343..1069633 + 291 WP_010308412.1 hypothetical protein -
EH203_RS04720 1069930..1070277 - 348 WP_004114521.1 hypothetical protein -
EH203_RS04725 1070301..1070528 - 228 WP_004114519.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
EH203_RS04730 1071159..1071686 - 528 WP_153266395.1 hypothetical protein -
EH203_RS04735 1072108..1072359 + 252 WP_005973616.1 prevent-host-death protein Antitoxin
EH203_RS04740 1072349..1072633 + 285 WP_005973612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EH203_RS21790 1073043..1073233 + 191 Protein_925 recombinase -
EH203_RS04745 1074566..1075213 - 648 WP_010308382.1 EcsC family protein -
EH203_RS04750 1075636..1076121 + 486 WP_161502189.1 Hcp family type VI secretion system effector -
EH203_RS04755 1076565..1077197 - 633 WP_161502190.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11010.96 Da        Isoelectric Point: 10.1716

>T115556 WP_005973612.1 NZ_CP034236:1072349-1072633 [Pectobacterium carotovorum subsp. carotovorum]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEHEIVVLVLAVGK
RERSEVYKTAKDRL

Download         Length: 285 bp

>T115556 NZ_CP034236:1072349-1072633 [Pectobacterium carotovorum subsp. carotovorum]
ATGAGTTATAAGCTGGAGTTTGAAGAGCACGCGCTGAAAGAATTTAAGAAGCTGGGTGCGCCCGTGCGGGAGCAGTTCAC
CAAAAAGTTGAAAGAGGTTTTACAAAATCCCCACGTTCCCGCCAACCGACTTCATGGAATGGCCGACTGCTATAAAATCA
AACTTCGTTCCGCTGGCTATCGGCTAGTGTATCAAGTGCTTGAACATGAGATCGTGGTACTGGTTTTAGCTGTGGGAAAA
CGTGAACGCTCAGAAGTTTATAAAACAGCCAAAGACCGACTATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9079.35 Da        Isoelectric Point: 5.0807

>AT115556 WP_005973616.1 NZ_CP034236:1072108-1072359 [Pectobacterium carotovorum subsp. carotovorum]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT115556 NZ_CP034236:1072108-1072359 [Pectobacterium carotovorum subsp. carotovorum]
ATGTCCGTACAACCTATCCTTGCGAATGCAGCCGTGAGTATCAGCGACTTTAAAAAATCGCCCAATGCCGCGCTTAAAGA
AGCTAACGGCGAGCCTGTAGCCGTGCTCACCAATGGCCGTATCTCTGGTTATTATGTTTCCCCGGAAACATGGGAAGCGC
TGGCCGATTATCAGGAAGATATCGAACTTGCCAAAATCGCCCGTTCTCGGATGAAGGGGAAACGTGTGAAGGTCGATCTG
GATGAGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z1B4

Antitoxin

Source ID Structure
AlphaFold DB A0A0G4JQP6

References