Detailed information of TA system TA115554

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-HTH_XRE
• Location: 130429..131134
• Replicon: chromosome
• Accession: NZ_CP034236
• Organism: Pectobacterium carotovorum subsp. carotovorum strain BP201601.1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EH203_RS00535
• Protein ID: WP_161502014.1
• Coordinates: 130709..131134 (-)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EH203_RS00530
• Protein ID: WP_103943792.1
• Coordinates: 130429..130728 (-)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EH203_RS00505	125664..126446	-	783	WP_161502011.1	hydroxypyruvate isomerase family protein	-
EH203_RS00510	126465..127124	-	660	WP_161502012.1	aldolase	-
EH203_RS00515	127121..128395	-	1275	WP_161502013.1	four-carbon acid sugar kinase family protein	-
EH203_RS00520	128392..129306	-	915	WP_014917036.1	NAD(P)-dependent oxidoreductase	-
EH203_RS00525	129645..130406	+	762	WP_010303245.1	DeoR/GlpR family DNA-binding transcription regulator	-
EH203_RS00530	130429..130728	-	300	WP_103943792.1	helix-turn-helix domain-containing protein	Antitoxin
EH203_RS00535	130709..131134	-	426	WP_161502014.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EH203_RS00545	131631..132325	+	695	Protein_107	hypothetical protein	-
EH203_RS00550	132327..132743	+	417	WP_125233371.1	hypothetical protein	-
EH203_RS00555	132854..133132	+	279	WP_161503028.1	DUF1778 domain-containing protein	-
EH203_RS00560	133210..133503	-	294	WP_010303225.1	type II toxin-antitoxin system RelE/ParE family toxin	-
EH203_RS00565	133496..133738	-	243	WP_010303222.1	type II toxin-antitoxin system ParD family antitoxin	-
EH203_RS00570	133934..135268	+	1335	WP_010303220.1	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (3-123)

Antitoxin

• Cro/C1-type helix-turn-helix domain (46-86)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15533.91 Da
• Isoelectric Point: 8.2499

>T115554 WP_161502014.1 NZ_CP034236:c131134-130709 [Pectobacterium carotovorum subsp. carotovorum]
VAVYTTKLFDKKLKSEILSDSYLCEIAHEVMNGRFEGDLGGGVIKKRIALNAGKSAGARTIIFFKLGSNLFFADGWKKNQ
VRKGVKEIQDDELAVYKDIAGDLLQLTVQQIAQLVKVKELREVECDGCKDERAAGNGEKPA

Nucleotide

• Length: 426 bp

>T115554 NZ_CP034236:c131134-130709 [Pectobacterium carotovorum subsp. carotovorum]
GTGGCGGTATACACGACAAAGCTCTTCGATAAAAAACTAAAAAGCGAAATACTTTCAGACAGTTACCTTTGTGAGATTGC
TCATGAGGTAATGAATGGTCGCTTTGAGGGTGACCTTGGCGGTGGTGTGATTAAGAAACGAATTGCATTGAATGCCGGAA
AGAGTGCAGGAGCCAGAACTATCATCTTTTTCAAACTGGGCTCTAATCTATTTTTTGCCGATGGATGGAAAAAAAATCAG
GTCAGGAAAGGCGTTAAAGAAATTCAGGATGATGAGCTGGCTGTTTATAAAGACATTGCTGGTGACCTACTTCAACTCAC
CGTTCAACAAATAGCTCAATTGGTAAAAGTGAAAGAACTACGAGAGGTGGAATGCGATGGCTGCAAAGATGAAAGAGCTG
CAGGAAATGGCGAAAAGCCTGCATGA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 11209.74 Da
• Isoelectric Point: 10.0902

>AT115554 WP_103943792.1 NZ_CP034236:c130728-130429 [Pectobacterium carotovorum subsp. carotovorum]
MAKSLHEHGGITDTTMERINNRVAAREFRERIEQAHAMSGAEIQNMRSRYKMSQSSLAYALNMSVESVSKWERNEKKPSG
AALRLLNIINEKGLDIFAS

Nucleotide

• Length: 300 bp

>AT115554 NZ_CP034236:c130728-130429 [Pectobacterium carotovorum subsp. carotovorum]
ATGGCGAAAAGCCTGCATGAACACGGGGGTATCACTGATACCACGATGGAACGCATTAATAATCGGGTTGCAGCACGGGA
ATTCCGTGAACGCATCGAGCAAGCTCACGCAATGAGCGGTGCAGAAATTCAGAACATGCGCTCCCGTTATAAAATGTCGC
AATCTTCTTTAGCTTACGCTCTCAATATGTCCGTTGAGAGCGTCTCAAAATGGGAACGGAATGAGAAGAAACCCTCAGGG
GCTGCGCTACGTCTTCTCAATATAATCAACGAGAAAGGTCTGGATATTTTTGCCAGTTAG