Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 435682..435914 Replicon chromosome
Accession NZ_CP034213
Organism Escherichia albertii strain NCTC 9362

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 435809..435912 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 435682..435914 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSB70_RS02210 430994..432235 + 1242 Protein_432 prolyl oligopeptidase family serine peptidase -
DSB70_RS02215 432232..432894 - 663 WP_025238865.1 exodeoxyribonuclease X -
DSB70_RS02220 432918..433574 - 657 WP_125059247.1 carbon-nitrogen hydrolase family protein YobB -
DSB70_RS02225 433676..433906 - 231 WP_000916758.1 DNA polymerase III subunit theta -
DSB70_RS02230 434045..434422 + 378 WP_000741562.1 CopC domain-containing protein YobA -
DSB70_RS02235 434426..435298 + 873 WP_059244199.1 copper homeostasis membrane protein CopD -
DSB70_RS02240 435311..435652 + 342 WP_000976487.1 DUF2511 domain-containing protein -
- 435682..435914 - 233 - - Antitoxin
- 435809..435912 + 104 - - Toxin
DSB70_RS02245 436534..437112 + 579 WP_164474073.1 bfpT-regulated chaperone -
DSB70_RS23655 437569..437733 + 165 WP_157944741.1 hypothetical protein -
DSB70_RS02255 438699..439011 + 313 Protein_441 potassium transporter TrkG -
DSB70_RS23660 439623..439826 + 204 WP_164474050.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 415144..457547 42403
- flank IS/Tn - - 439027..439530 503


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T115509 NZ_CP034213:435809-435912 [Escherichia albertii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAAAAC
AGGAATCGTTTTCGGTCTCTTTTT

Antitoxin


Download         Length: 233 bp

>AT115509 NZ_CP034213:c435914-435682 [Escherichia albertii]
ATAAAAAGAGACCGAAAACGATTCCTGTTTTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTACAAAATGGTCAG
TAAAAAGCGCGTCGGCCATCGTCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGTGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References