Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | slvAT/RES(toxin) |
| Location | 3897409..3898307 | Replicon | chromosome |
| Accession | NZ_CP034179 | ||
| Organism | Novosphingobium tardaugens NBRC 16725 | ||
Toxin (Protein)
| Gene name | slvT | Uniprot ID | U2YM43 |
| Locus tag | EGO55_RS18365 | Protein ID | WP_021690670.1 |
| Coordinates | 3897780..3898307 (+) | Length | 176 a.a. |
Antitoxin (Protein)
| Gene name | slvA | Uniprot ID | - |
| Locus tag | EGO55_RS18360 | Protein ID | WP_124916881.1 |
| Coordinates | 3897409..3897783 (+) | Length | 125 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGO55_RS18340 | 3892999..3893751 | + | 753 | WP_021690675.1 | creatininase family protein | - |
| EGO55_RS18345 | 3893896..3894372 | + | 477 | WP_040716090.1 | hypothetical protein | - |
| EGO55_RS18350 | 3894407..3895546 | + | 1140 | WP_052023713.1 | phosphoadenosine phosphosulfate reductase family protein | - |
| EGO55_RS18355 | 3895611..3897299 | + | 1689 | WP_040716087.1 | ATP-binding protein | - |
| EGO55_RS18360 | 3897409..3897783 | + | 375 | WP_124916881.1 | hypothetical protein | Antitoxin |
| EGO55_RS18365 | 3897780..3898307 | + | 528 | WP_021690670.1 | RES family NAD+ phosphorylase | Toxin |
| EGO55_RS18370 | 3898360..3898566 | + | 207 | WP_021690669.1 | hypothetical protein | - |
| EGO55_RS18375 | 3898764..3899033 | + | 270 | WP_021690668.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| EGO55_RS18380 | 3899033..3899326 | + | 294 | WP_021690667.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EGO55_RS18385 | 3899401..3900561 | + | 1161 | WP_210766570.1 | hypothetical protein | - |
| EGO55_RS18390 | 3900643..3901143 | + | 501 | WP_021690665.1 | hypothetical protein | - |
| EGO55_RS18395 | 3901307..3901987 | + | 681 | WP_040716233.1 | NYN domain-containing protein | - |
| EGO55_RS18400 | 3902123..3902338 | + | 216 | WP_040716230.1 | hypothetical protein | - |
| EGO55_RS18405 | 3902866..3903198 | + | 333 | WP_210766571.1 | antibiotic biosynthesis monooxygenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 176 a.a. Molecular weight: 19178.56 Da Isoelectric Point: 6.0890
>T115461 WP_021690670.1 NZ_CP034179:3897780-3898307 [Novosphingobium tardaugens NBRC 16725]
VKVRALGPDDVFYRYLTPKWAFVPLSGAGAAAEGGRFNRGGIEALYLARAPQTALEEYAQDSSLVRPATLASYLLSVESI
VDLSGGYDPDHWSGDWAEWDCPWRRIVRIDKGTPSSWLLADKVISDGHKGILFPSIRHPGGTNLVIFNSNLAAADRMTVH
DPDGRLPKDQSSWPS
VKVRALGPDDVFYRYLTPKWAFVPLSGAGAAAEGGRFNRGGIEALYLARAPQTALEEYAQDSSLVRPATLASYLLSVESI
VDLSGGYDPDHWSGDWAEWDCPWRRIVRIDKGTPSSWLLADKVISDGHKGILFPSIRHPGGTNLVIFNSNLAAADRMTVH
DPDGRLPKDQSSWPS
Download Length: 528 bp
>T115461 NZ_CP034179:3897780-3898307 [Novosphingobium tardaugens NBRC 16725]
GTGAAGGTCAGGGCGCTTGGTCCCGACGACGTCTTCTATCGCTACCTCACCCCCAAATGGGCTTTCGTGCCCCTGAGCGG
TGCGGGCGCGGCAGCGGAAGGCGGTCGCTTCAACCGGGGCGGCATCGAAGCGCTCTATCTGGCGCGGGCGCCGCAGACCG
CGCTGGAGGAATATGCCCAGGACTCCTCGCTGGTCCGGCCCGCGACATTGGCCAGCTACCTGCTCTCGGTGGAGAGCATC
GTCGATCTTTCTGGCGGCTACGATCCGGACCATTGGTCTGGCGATTGGGCGGAATGGGATTGTCCGTGGCGGCGGATCGT
GCGGATTGACAAGGGAACGCCGTCGTCCTGGCTACTGGCCGACAAAGTCATCTCGGATGGCCACAAGGGCATCCTCTTTC
CTTCGATCCGGCATCCGGGCGGCACAAACCTCGTAATCTTCAACTCGAACCTTGCCGCTGCCGATCGAATGACGGTTCAC
GATCCCGATGGCCGCTTGCCCAAGGACCAGTCTTCCTGGCCCAGTTGA
GTGAAGGTCAGGGCGCTTGGTCCCGACGACGTCTTCTATCGCTACCTCACCCCCAAATGGGCTTTCGTGCCCCTGAGCGG
TGCGGGCGCGGCAGCGGAAGGCGGTCGCTTCAACCGGGGCGGCATCGAAGCGCTCTATCTGGCGCGGGCGCCGCAGACCG
CGCTGGAGGAATATGCCCAGGACTCCTCGCTGGTCCGGCCCGCGACATTGGCCAGCTACCTGCTCTCGGTGGAGAGCATC
GTCGATCTTTCTGGCGGCTACGATCCGGACCATTGGTCTGGCGATTGGGCGGAATGGGATTGTCCGTGGCGGCGGATCGT
GCGGATTGACAAGGGAACGCCGTCGTCCTGGCTACTGGCCGACAAAGTCATCTCGGATGGCCACAAGGGCATCCTCTTTC
CTTCGATCCGGCATCCGGGCGGCACAAACCTCGTAATCTTCAACTCGAACCTTGCCGCTGCCGATCGAATGACGGTTCAC
GATCCCGATGGCCGCTTGCCCAAGGACCAGTCTTCCTGGCCCAGTTGA
Antitoxin
Download Length: 125 a.a. Molecular weight: 13531.33 Da Isoelectric Point: 7.4022
>AT115461 WP_124916881.1 NZ_CP034179:3897409-3897783 [Novosphingobium tardaugens NBRC 16725]
MERRTTAISGFVESLQEPRTPYISPKRFSAALGIQVAGLANLAGVHRNTMRNPASERLQDKLREMVRVIAAAATLTGDVS
KAIFWYRNEPIADYDHKTAAELVAEGHADAVMAHLRDLENGASG
MERRTTAISGFVESLQEPRTPYISPKRFSAALGIQVAGLANLAGVHRNTMRNPASERLQDKLREMVRVIAAAATLTGDVS
KAIFWYRNEPIADYDHKTAAELVAEGHADAVMAHLRDLENGASG
Download Length: 375 bp
>AT115461 NZ_CP034179:3897409-3897783 [Novosphingobium tardaugens NBRC 16725]
ATGGAGCGCCGCACGACCGCCATATCGGGGTTCGTCGAGAGCCTCCAGGAACCGCGCACGCCTTATATTTCTCCCAAGCG
TTTTTCCGCGGCGTTGGGGATCCAGGTTGCGGGCCTCGCCAATCTCGCTGGCGTCCATCGCAATACCATGCGCAATCCGG
CCTCCGAGCGCCTGCAGGACAAGCTTCGGGAAATGGTGCGGGTCATCGCCGCGGCTGCCACGCTGACCGGCGACGTGTCC
AAGGCGATCTTCTGGTACCGCAACGAGCCCATCGCCGATTACGATCACAAGACCGCCGCCGAACTTGTGGCGGAGGGGCA
TGCCGACGCGGTGATGGCGCATCTGCGTGATCTCGAAAACGGCGCCAGCGGGTGA
ATGGAGCGCCGCACGACCGCCATATCGGGGTTCGTCGAGAGCCTCCAGGAACCGCGCACGCCTTATATTTCTCCCAAGCG
TTTTTCCGCGGCGTTGGGGATCCAGGTTGCGGGCCTCGCCAATCTCGCTGGCGTCCATCGCAATACCATGCGCAATCCGG
CCTCCGAGCGCCTGCAGGACAAGCTTCGGGAAATGGTGCGGGTCATCGCCGCGGCTGCCACGCTGACCGGCGACGTGTCC
AAGGCGATCTTCTGGTACCGCAACGAGCCCATCGCCGATTACGATCACAAGACCGCCGCCGAACTTGTGGCGGAGGGGCA
TGCCGACGCGGTGATGGCGCATCTGCGTGATCTCGAAAACGGCGCCAGCGGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|