Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 59491..60016 Replicon plasmid unnamed
Accession NZ_CP034178
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000189

Toxin (Protein)


Gene name ccdB Uniprot ID A0A4D6P1W7
Locus tag EB813_RS23030 Protein ID WP_020833585.1
Coordinates 59491..59796 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID I3VZQ6
Locus tag EB813_RS23035 Protein ID WP_000813642.1
Coordinates 59798..60016 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EB813_RS23010 54529..55734 - 1206 WP_000427674.1 AAA family ATPase -
EB813_RS23015 56423..56677 - 255 WP_001749329.1 hypothetical protein -
EB813_RS23020 57308..58249 + 942 WP_000728920.1 Rpn family recombination-promoting nuclease/putative transposase -
EB813_RS23025 58400..59182 - 783 WP_020833584.1 site-specific integrase -
EB813_RS23030 59491..59796 - 306 WP_020833585.1 type II toxin-antitoxin system toxin CcdB Toxin
EB813_RS23035 59798..60016 - 219 WP_000813642.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
EB813_RS23040 60836..61207 - 372 WP_100215268.1 DUF1311 domain-containing protein -
EB813_RS23045 61995..62717 - 723 WP_000742239.1 LuxR C-terminal-related transcriptional regulator -
EB813_RS23050 62916..63968 - 1053 WP_020833588.1 Ig-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81814 81814


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 15030.03 Da        Isoelectric Point: 5.5500

>T115456 WP_020833585.1 NZ_CP034178:c59796-59491 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Download         Length: 306 bp

>T115456 NZ_CP034178:c59796-59491 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 10761.91 Da        Isoelectric Point: 5.5500

>AT115456 WP_000813642.1 NZ_CP034178:c60016-59798 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 219 bp

>AT115456 NZ_CP034178:c60016-59798 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D6P1W7

Antitoxin

Source ID Structure
AlphaFold DB A0A600YYQ0

References