Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 1848..2395 Replicon plasmid unnamed
Accession NZ_CP034178
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000189

Toxin (Protein)


Gene name parE Uniprot ID A0A4D6NZF1
Locus tag EB813_RS22710 Protein ID WP_000970006.1
Coordinates 1848..2129 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A4D6P197
Locus tag EB813_RS22715 Protein ID WP_000084547.1
Coordinates 2126..2395 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EB813_RS22705 1106..1696 + 591 WP_031607984.1 plasmid pRiA4b ORF-3 family protein -
EB813_RS22710 1848..2129 - 282 WP_000970006.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
EB813_RS22715 2126..2395 - 270 WP_000084547.1 hypothetical protein Antitoxin
EB813_RS22720 3351..4232 - 882 WP_023193063.1 incFII family plasmid replication initiator RepA -
EB813_RS22725 4213..4290 - 78 WP_001541552.1 RepA leader peptide Tap -
EB813_RS22730 4540..4806 - 267 WP_001576653.1 replication regulatory protein RepA -
EB813_RS22735 4950..5420 - 471 Protein_6 phospholipase D family protein -
EB813_RS22740 5660..6391 - 732 WP_020833545.1 type-F conjugative transfer system pilin acetylase TraX -
EB813_RS22745 6388..6954 - 567 WP_000493830.1 DUF2726 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81814 81814


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T115455 WP_000970006.1 NZ_CP034178:c2129-1848 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T115455 NZ_CP034178:c2129-1848 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 13263.91 Da        Isoelectric Point: 5.5500

>AT115455 WP_000084547.1 NZ_CP034178:c2395-2126 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Download         Length: 270 bp

>AT115455 NZ_CP034178:c2395-2126 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D6NZF1

Antitoxin

Source ID Structure
AlphaFold DB A0A4D6P197

References