Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1488488..1489075 Replicon chromosome
Accession NZ_CP034171
Organism Chryseobacterium taklimakanense strain H4753

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EIH08_RS06930 Protein ID WP_124784682.1
Coordinates 1488776..1489075 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3G8WVU0
Locus tag EIH08_RS06925 Protein ID WP_055041555.1
Coordinates 1488488..1488772 (-) Length 95 a.a.

Genomic Context

EIH08_RS06905EIH08_RS06935EIH08_RS06940EIH08_RS06910EIH08_RS06915EIH08_RS12590EIH08_RS06925EIH08_RS06930EIH08_RS06950EIH08_RS06955
Location: 1484349..1485649 (1301 bp)
Type: Others
Protein ID: Protein_1367
Location: 1489518..1490429 (912 bp)
Type: Others
Protein ID: WP_124784683.1
Location: 1490413..1491531 (1119 bp)
Type: Others
Protein ID: WP_124784684.1
Location: 1485685..1486635 (951 bp)
Type: Others
Protein ID: WP_124784680.1
Location: 1487236..1487760 (525 bp)
Type: Others
Protein ID: WP_124784681.1
Location: 1487989..1488318 (330 bp)
Type: Others
Protein ID: WP_164466710.1
Location: 1488488..1488772 (285 bp)
Type: Antitoxin
Protein ID: WP_055041555.1
Location: 1488776..1489075 (300 bp)
Type: Toxin
Protein ID: WP_124784682.1
Location: 1492069..1492304 (236 bp)
Type: Others
Protein ID: Protein_1375
Location: 1492415..1493434 (1020 bp)
Type: Others
Protein ID: WP_124784685.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EIH08_RS069051484349..1485649+1301Protein_1367IS5 family transposase-
EIH08_RS069101485685..1486635-951WP_124784680.1hypothetical protein-
EIH08_RS069151487236..1487760-525WP_124784681.1hypothetical protein-
EIH08_RS125901487989..1488318-330WP_164466710.1hypothetical protein-
EIH08_RS069251488488..1488772-285WP_055041555.1putative addiction module antidote proteinAntitoxin
EIH08_RS069301488776..1489075-300WP_124784682.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EIH08_RS069351489518..1490429+912WP_124784683.1tyrosine-type recombinase/integrase-
EIH08_RS069401490413..1491531+1119WP_124784684.1IS91 family transposase-
EIH08_RS069501492069..1492304-236Protein_1375hypothetical protein-
EIH08_RS069551492415..1493434-1020WP_124784685.1glycosyl hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11798.76 Da        Isoelectric Point: 10.0546

>T115452 WP_124784682.1 NZ_CP034171:c1489075-1488776 [Chryseobacterium taklimakanense]
MYFIEKTNEFDKWFRKLKDIRAKAKILFRIQKLQNEEHFGDCKPVGNGISELRINFAKGYRIYFKETDGKIIILLIGGDK
SSQQKDIEKAKEIWEKIKE

Download         Length: 300 bp

>T115452 NZ_CP034171:c1489075-1488776 [Chryseobacterium taklimakanense]
ATGTACTTTATTGAGAAAACAAATGAGTTTGACAAGTGGTTTCGAAAATTAAAAGATATCCGAGCAAAGGCTAAAATCTT
GTTCCGAATCCAGAAGTTACAAAACGAAGAACATTTTGGAGATTGCAAACCTGTTGGAAATGGAATCAGCGAATTGCGAA
TAAATTTTGCAAAGGGCTACAGAATCTATTTCAAAGAGACAGATGGAAAAATTATTATCTTGTTAATTGGCGGCGACAAA
TCAAGCCAACAAAAAGATATAGAAAAAGCGAAAGAAATTTGGGAAAAAATAAAAGAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10136.69 Da        Isoelectric Point: 4.2958

>AT115452 WP_055041555.1 NZ_CP034171:c1488772-1488488 [Chryseobacterium taklimakanense]
MDISKFDIADYLDSNEMIAEYLNVVLEEGDDSEIVVAIGNIAKAIGMTKIAEETGMSRPSLYKALSEGAKPQFSTIMKVL
KAVGGQIRVNPITA

Download         Length: 285 bp

>AT115452 NZ_CP034171:c1488772-1488488 [Chryseobacterium taklimakanense]
ATGGATATTTCAAAATTTGACATTGCAGATTATTTGGACAGCAACGAAATGATTGCTGAATATCTTAATGTTGTCCTTGA
AGAAGGCGATGATTCTGAAATTGTTGTAGCAATTGGTAATATTGCAAAAGCAATCGGAATGACAAAAATTGCAGAAGAAA
CAGGAATGAGCAGACCGAGTTTGTACAAAGCACTTTCTGAAGGTGCAAAACCACAGTTTTCAACAATTATGAAAGTTTTG
AAAGCAGTTGGCGGACAAATAAGAGTTAATCCTATAACTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3G8WVU0

References