Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 150495..151030 Replicon plasmid pPagL15_2
Accession NZ_CP034150
Organism Pantoea agglomerans strain L15

Toxin (Protein)


Gene name relE Uniprot ID A0A8X8DPA1
Locus tag CBF16_RS22540 Protein ID WP_010257115.1
Coordinates 150743..151030 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CBF16_RS22535 Protein ID WP_039387444.1
Coordinates 150495..150746 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBF16_RS22515 146098..146367 - 270 WP_010257103.1 DUF1471 domain-containing protein -
CBF16_RS22520 146643..147779 - 1137 WP_033786324.1 HlyD family secretion protein -
CBF16_RS22525 147781..148107 - 327 WP_010257107.1 DUF3302 domain-containing protein -
CBF16_RS22530 148702..150354 + 1653 WP_124890821.1 intermembrane transport protein PqiB -
CBF16_RS22535 150495..150746 + 252 WP_039387444.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CBF16_RS22540 150743..151030 + 288 WP_010257115.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CBF16_RS22545 151304..151594 - 291 WP_022624282.1 helix-turn-helix domain-containing protein -
CBF16_RS22550 151591..151923 - 333 WP_031292300.1 type II toxin-antitoxin system RelE/ParE family toxin -
CBF16_RS22560 152473..152685 + 213 Protein_124 haloacid dehalogenase type II -
CBF16_RS22565 152790..153155 - 366 WP_124890823.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase -
CBF16_RS22570 153152..153472 - 321 WP_010257131.1 EamA family transporter -
CBF16_RS22575 153472..155139 - 1668 WP_124890825.1 lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..179590 179590


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11173.08 Da        Isoelectric Point: 10.3856

>T115384 WP_010257115.1 NZ_CP034150:150743-151030 [Pantoea agglomerans]
VSYTVKFREEAFKEWQKLDKSLQQQFAKKLKKCCDNPHIPSARLRGIKDCYKIKLRASGFRLVYQVIDDQLVIAVVAVGK
RERSDVYHLASERMR

Download         Length: 288 bp

>T115384 NZ_CP034150:150743-151030 [Pantoea agglomerans]
GTGAGTTATACCGTCAAATTCAGGGAAGAGGCATTTAAAGAATGGCAGAAGCTGGACAAATCTCTCCAGCAGCAGTTTGC
CAAAAAACTGAAGAAATGTTGTGACAATCCCCATATTCCTTCTGCCAGACTACGTGGGATTAAAGACTGCTATAAAATCA
AACTCAGAGCGTCCGGGTTTCGCCTGGTTTATCAGGTAATAGACGACCAGCTGGTGATTGCCGTTGTTGCTGTGGGTAAA
CGCGAGCGCAGCGATGTTTATCATCTTGCCAGTGAGAGGATGCGGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9108.38 Da        Isoelectric Point: 3.9507

>AT115384 WP_039387444.1 NZ_CP034150:150495-150746 [Pantoea agglomerans]
MPNIILSDTSASVSELKKNPMATVNAGDGYPVAILNRNQPAFYCVPAELYEQMLDALDDQELVKLVSERSGQRLLDVDLD
ALL

Download         Length: 252 bp

>AT115384 NZ_CP034150:150495-150746 [Pantoea agglomerans]
ATGCCAAACATTATTTTAAGCGATACCAGTGCCAGCGTAAGCGAACTGAAGAAAAATCCAATGGCCACGGTTAATGCAGG
TGACGGTTATCCTGTCGCCATTCTTAACCGCAACCAGCCTGCATTCTATTGCGTCCCGGCTGAGCTTTATGAACAGATGC
TTGATGCCCTTGACGATCAGGAACTGGTTAAGCTGGTCAGTGAGCGCAGCGGCCAGCGTCTGCTTGATGTCGATTTGGAT
GCGCTTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References