Detailed information of TA system TA115383

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 115170..115696
• Replicon: plasmid pPagL15_2
• Accession: NZ_CP034150
• Organism: Pantoea agglomerans strain L15

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CBF16_RS22375
• Protein ID: WP_124890797.1
• Coordinates: 115170..115457 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A8X8DPB7
• Locus tag: CBF16_RS22380
• Protein ID: WP_010257033.1
• Coordinates: 115457..115696 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CBF16_RS22355	111258..112283	-	1026	WP_033759924.1	alpha/beta hydrolase	-
CBF16_RS22360	112352..113545	-	1194	WP_033770135.1	MFS transporter	-
CBF16_RS22365	113679..114575	+	897	WP_124890796.1	LysR family transcriptional regulator	-
CBF16_RS22370	114639..114815	-	177	WP_010257023.1	stress-induced protein	-
CBF16_RS22375	115170..115457	-	288	WP_124890797.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CBF16_RS22380	115457..115696	-	240	WP_010257033.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CBF16_RS22385	116056..118029	+	1974	WP_124890798.1	FIST C-terminal domain-containing protein	-
CBF16_RS22390	118134..119150	+	1017	WP_124890799.1	NAD(P)-dependent alcohol dehydrogenase	-
CBF16_RS22395	119200..119868	-	669	WP_031292291.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	-	1..179590	179590

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-77)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10977.81 Da
• Isoelectric Point: 10.1604

>T115383 WP_124890797.1 NZ_CP034150:c115457-115170 [Pantoea agglomerans]
MTWQLEFDQRALKEWRKLGPTVREQLKKKLAECLESPRIEANKLSGMPDCYKIKLKSSGYRLVYQVIDDRVVVFVVAVGK
RERSEVYSAASGRLS

Nucleotide

• Length: 288 bp

>T115383 NZ_CP034150:c115457-115170 [Pantoea agglomerans]
ATGACCTGGCAACTGGAGTTCGATCAGAGGGCACTGAAAGAGTGGCGCAAGCTGGGCCCGACAGTACGTGAACAGCTTAA
AAAGAAGCTGGCTGAGTGTCTTGAGTCACCCAGAATTGAGGCGAACAAACTCAGCGGGATGCCTGACTGCTATAAGATCA
AGCTAAAGTCATCCGGTTATCGACTTGTATACCAGGTTATTGATGACCGGGTGGTGGTTTTTGTGGTGGCTGTCGGGAAA
AGAGAGCGCTCAGAGGTTTATTCTGCCGCTTCCGGGCGTCTCTCTTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9002.33 Da
• Isoelectric Point: 4.3410

>AT115383 WP_010257033.1 NZ_CP034150:c115696-115457 [Pantoea agglomerans]
MGTINIRIDDDLKTRSYAALEKMGVTPSDALRLMLEYIADNERLPFKQTLLSDEDAALVDIVKERLRNPEPVRVTLDDL

Nucleotide

• Length: 240 bp

>AT115383 NZ_CP034150:c115696-115457 [Pantoea agglomerans]
ATGGGCACAATTAACATTCGAATCGATGATGACCTGAAGACACGATCCTATGCTGCGCTCGAAAAAATGGGTGTGACTCC
TTCTGATGCGCTGCGCCTGATGCTTGAATATATTGCAGATAATGAACGTCTTCCCTTTAAGCAAACGTTACTCAGTGACG
AAGATGCGGCGTTGGTAGACATAGTTAAAGAACGCCTGCGAAACCCTGAGCCTGTCCGGGTCACACTGGATGACCTTTAA