Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2091369..2092525 Replicon chromosome
Accession NZ_CP034142
Organism Marinobacter sp. NP-4(2019)

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EHN06_RS09625 Protein ID WP_127332354.1
Coordinates 2091369..2092163 (-) Length 265 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EHN06_RS09630 Protein ID WP_127332356.1
Coordinates 2092160..2092525 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHN06_RS09590 2086413..2087024 - 612 WP_127332344.1 membrane integrity-associated transporter subunit PqiC -
EHN06_RS09595 2087021..2087959 - 939 WP_127332346.1 MCE family protein -
EHN06_RS09600 2087962..2088753 - 792 WP_127332348.1 ABC transporter ATP-binding protein -
EHN06_RS09605 2088756..2089928 - 1173 WP_127332350.1 ABC transporter permease -
EHN06_RS09620 2090379..2091233 - 855 WP_127332352.1 phosphotransferase -
EHN06_RS09625 2091369..2092163 - 795 WP_127332354.1 RES family NAD+ phosphorylase Toxin
EHN06_RS09630 2092160..2092525 - 366 WP_127332356.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
EHN06_RS09635 2092594..2093250 - 657 WP_127332358.1 transglutaminase-like cysteine peptidase -
EHN06_RS09640 2093259..2093912 - 654 WP_127332360.1 general secretion pathway protein GspC -
EHN06_RS09645 2094105..2095613 + 1509 WP_127332362.1 type II secretion system ATPase GspE -
EHN06_RS09650 2095618..2096832 + 1215 WP_127332364.1 type II secretion system inner membrane protein GspF -
EHN06_RS09655 2096894..2097358 + 465 WP_127332366.1 type II secretion system major pseudopilin GspG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(60-222)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-119)


Sequences

Toxin        


Download         Length: 265 a.a.        Molecular weight: 29777.99 Da        Isoelectric Point: 9.1653

>T115366 WP_127332354.1 NZ_CP034142:c2092163-2091369 [Marinobacter sp. NP-4(2019)]
MSLRDRIESSITVVQGTTYRVVESQEEIATTELVANIQEQMRLEELLEQSKPPRPEGTEGLHYLLATPFRYPPLKYGSRF
GRPFEKSLFYGAMTVNTTLAEAAFYRFVFISDMVVPYPKPLKTLHTLFATRVRTSRGVRLQDKTWEDLHDALTNPASYDA
CQNLGTTMRESGIEGFQFLSARARQAGLYELPYSPAKGLEGVNAALFSPRALKDRKPRSRYRLIMMADPTTVTMSLTNEE
GRKTASAFSRDTFLVDGRLPCPAS

Download         Length: 795 bp

>T115366 NZ_CP034142:c2092163-2091369 [Marinobacter sp. NP-4(2019)]
TTGAGCCTGCGCGATCGCATCGAGTCCAGCATCACCGTGGTGCAGGGTACGACCTACCGGGTGGTCGAATCCCAGGAAGA
GATAGCCACCACGGAACTGGTGGCTAACATTCAGGAGCAGATGAGGCTTGAGGAACTTCTGGAGCAGAGCAAACCGCCGC
GACCGGAAGGCACCGAAGGCCTCCACTATTTGTTGGCAACACCCTTTCGCTACCCTCCCCTGAAATACGGTTCGCGTTTT
GGTCGCCCCTTCGAGAAAAGCCTGTTTTACGGGGCCATGACGGTTAATACCACCCTGGCAGAAGCCGCGTTCTATCGCTT
TGTATTTATCAGCGATATGGTCGTACCCTACCCCAAGCCCCTGAAAACCCTCCATACCCTTTTTGCCACCCGGGTGCGCA
CCAGTCGCGGTGTTCGCCTGCAGGATAAGACCTGGGAAGATCTCCACGACGCGTTGACCAATCCCGCCAGCTACGATGCC
TGCCAAAATCTCGGGACAACCATGAGGGAATCGGGAATCGAGGGGTTTCAGTTCCTGTCAGCCCGGGCACGCCAGGCCGG
CCTCTATGAGTTGCCATACTCACCGGCAAAAGGCCTCGAAGGTGTCAACGCAGCGTTGTTTTCACCACGGGCACTGAAAG
ACAGGAAACCCAGGAGTCGCTATCGCCTGATTATGATGGCAGACCCGACCACCGTGACCATGAGCCTGACCAACGAAGAG
GGCAGGAAAACTGCCTCAGCTTTCAGTCGGGACACCTTTCTGGTGGATGGCAGGCTGCCGTGCCCGGCGAGCTAG

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13417.39 Da        Isoelectric Point: 9.3908

>AT115366 WP_127332356.1 NZ_CP034142:c2092525-2092160 [Marinobacter sp. NP-4(2019)]
MTTVSDIKQQTTDRALLGKAVVNAGKAMGLTQTDVAEIVGRNRSGLVRDGIDPSSKAGELALLFIRLYRSVYALVGGDEE
AMRHWLNTENRYFSDVPRELVRSAEGLVRVLYYLDAMRGKI

Download         Length: 366 bp

>AT115366 NZ_CP034142:c2092525-2092160 [Marinobacter sp. NP-4(2019)]
ATGACCACCGTTTCAGACATAAAACAGCAAACCACCGACCGTGCACTGCTGGGCAAAGCCGTGGTCAATGCCGGCAAGGC
CATGGGCCTGACCCAGACAGACGTGGCCGAGATTGTGGGTCGCAACCGCTCCGGCCTGGTCCGGGACGGCATCGATCCCT
CCAGCAAGGCCGGCGAACTTGCCCTGCTTTTCATCCGCCTGTATCGCAGCGTGTATGCGCTTGTAGGTGGGGATGAGGAG
GCCATGCGGCATTGGCTCAACACCGAAAACCGGTACTTCTCCGATGTACCCAGAGAGCTGGTTCGCAGTGCAGAAGGGCT
GGTGCGGGTGCTTTATTACCTTGACGCCATGCGAGGCAAGATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References